Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Quadro‑Iliac Plane Block versus Erector Spinae Plane for pain after total hip replacement

Official title: Analgesic Efficacy of Quadro-Iliac Plane Block Versus Erector Spinae Plane in Total Hip Arthroplasty: A Randomized Non-Inferiority Trial

Run by Tanta University · NCT07537036 · Data updated 2026-11-12

This will test whether the quadro‑iliac plane block or the erector spinae plane block controls pain better after total hip replacement in adults having spinal anesthesia.

More Erector Spinae Plane Block trials

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment76 (estimated)
SponsorTanta University
Academic / other
Locations1 site (Tanta, El-Gharbia)
StatusRecruiting
StartedApril 18, 2026
Main results expectedNovember 30, 2026
Study endsNovember 30, 2026
Registry record updatedJune 23, 2026
Trial IDNCT07537036 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 18 or older scheduled for elective total hip arthroplasty under spinal anesthesia with ASA physical status I–III, BMI ≤ 35 kg/m2, no opioid dependency, and no contraindications to local anesthetics.

Probably not a fit

Patients with allergies to local anesthetics, opioid dependency, BMI > 35, cognitive impairment, bleeding/coagulation disorders, local infection at the injection site, severe organ dysfunction, psychiatric or neurological disorders, or those undergoing emergency surgery may not benefit or be eligible.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Total hip arthroplasty is commonly performed and effective postoperative pain control is important to minimize opioid use and its side effects. This interventional comparison applies either a quadro‑iliac plane block (QIPB) or an erector spinae plane block (ESPB) after THA performed under spinal anesthesia. Participants will receive one of the two regional blocks and postoperative pain, opioid consumption, and related side effects will be monitored. The aim is to determine which block provides superior analgesia and fewer opioid-related complications for adult patients.

Why it matters

Potential benefit: If successful, one block could provide better pain relief with lower opioid use and fewer opioid-related side effects after hip replacement.

How similar studies have gone: Fascial plane blocks such as ESPB and various quadratus/iliac approaches have shown opioid-sparing and pain-reducing effects in some studies, but the quadro‑iliac plane block is relatively new and direct head-to-head evidence is limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥ 18 years.
* Both sexes.
* American Society of Anesthesiology (ASA) physical status I-III.
* Undergoing total hip arthroplasty (THA) under spinal anesthesia.

Exclusion Criteria:

* History of allergies to local anesthetics.
* Opioid dependency.
* Body mass index (BMI) \> 35 kg/m2.
* Cognitive impairment.
* Bleeding or coagulation disorders.
* Psychiatric and neurological disorder.
* Local infection at the site of injection.
* Severe heart, lung, liver, and renal dysfunction.
* Emergency surgery.

Where it's running

  • Tanta University
    Tanta, El-Gharbia, Egypt
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.