Computer-based cognitive training for people with multiple sclerosis

Testing the Feasibility of Computer-based Cognitive Training in Individuals with Multiple Sclerosis Living in the Community

Not applicable Interventional Kessler Foundation · NCT06608797

This study is testing a computer-based training program to see if it can help people with multiple sclerosis improve their memory and learning skills from home.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment40 (estimated)
Ages19 Years to 65 Years
SexAll
SponsorKessler Foundation Academic / other
Locations1 site (East Hanover, New Jersey)
Trial IDNCT06608797 on ClinicalTrials.gov

What this trial studies

This study evaluates the feasibility of a computer-based cognitive training program designed to improve learning and memory in individuals diagnosed with multiple sclerosis (MS). The intervention consists of 10 sessions aimed at enhancing cognitive performance, daily life activities, and neuroimaging outcomes. Given the challenges of transportation to clinical settings, this pilot study seeks to determine the effectiveness of delivering cognitive training remotely to address these barriers. Participants will be assessed for eligibility based on specific cognitive impairments and other health criteria.

Who should consider this trial

Good fit: Ideal candidates are individuals diagnosed with multiple sclerosis who exhibit impaired learning and memory abilities.

Not a fit: Patients who have had a recent exacerbation of MS or those with significant neurological or psychiatric conditions may not benefit from this study.

Why it matters

Potential benefit: If successful, this program could significantly improve cognitive function and quality of life for individuals with multiple sclerosis.

How similar studies have performed: Previous studies have shown positive outcomes with similar cognitive training approaches, suggesting potential for success in this pilot study.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* English as primary language
* Diagnosis of multiple sclerosis

Exclusion Criteria:

* Most recent exacerbation within one month
* Other Neurological History: head injury, stroke, seizures, or any other significant neurological history will not be included in the study
* Individuals with an active diagnosis of Major Depressive Disorder, Schizophrenia, Bipolar Disorder I or II will be excluded from the study.
* Poor Visual Acuity (corrected vision in worse eye \< 20/60), diplopia, or nystagmus
* Inability to understand directions and following one, two, and three step commands
* Intact New Learning and Memory: Only individuals that show impaired performance on a memory test will be included in the study

Where this trial is running

East Hanover, New Jersey

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Multiple Sclerosislearning, memory, cognitive training
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.