Comparison of two approaches for tibial nail surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized trial compares two surgical approaches for intramedullary nailing of tibial shaft fractures. Adults aged 18 to 60 with acute tibial shaft fractures are assigned to either the medial parapatellar or the transpatellar approach, with all procedures performed by experienced orthopedic surgeons. Primary outcome is functional recovery measured by the Lower Extremity Functional Scale (LEFS); secondary outcomes include postoperative pain and knee motion. The study aims to determine if one approach yields superior knee function and overall recovery after surgery. Participants are followed under standardized operative and postoperative protocols at a single center in Lahore, Pakistan.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults aged 18 to 60 years, irrespective of sex.
* Patients with an acute tibial shaft fracture confirmed by radiographic examination.
* Gustilo-Anderson type I, II, or IIIA open fractures.
* Patients who are eligible for intramedullary interlocking nailing according to the treating orthopedic surgeon.
* Patients willing and able to provide written informed consent.

Exclusion Criteria:

* Previous fracture or surgery involving the affected tibia.
* Osteoporosis or other conditions significantly affecting bone healing.
* Diabetes mellitus, peripheral vascular disease, autoimmune disorders, or other systemic conditions that may adversely affect bone healing or postoperative recovery.
* Neurovascular injury involving the affected limb.

Where it's running

• Jinnah Hospital Lahore
  Lahore, Punjab Province, Pakistan Recruiting

Study contacts

• Principal investigator: Prof. Sajjad Hussain — Aimc
• Study coordinator: Prof. Sajjad Hussain
• Email: prof.sajjadhussain@aimc.edu.pk
• Phone: 0333 4077389

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.