Monitoring leg pressure in teens with tibia fractures
Official title: Continuous Compartment Pressure Monitoring in Adolescent Tibia Fractures
Run by Boston Children's Hospital · NCT07674043 · Data updated 2026-11-12
A sensor is placed during surgery to see if measuring anterior leg pressure can help doctors spot acute compartment syndrome in teens with tibia fractures.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 10 Years to 21 Years |
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | Boston Children's Hospital Academic / other |
| Locations | 1 site (Boston, Massachusetts) |
| Status | Recruiting |
| Started | August 17, 2026 |
| Main results expected | June 1, 2028 |
| Study ends | June 1, 2028 |
| Registry record updated | October 23, 2026 |
| Trial ID | NCT07674043 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are patients aged 10–21 undergoing operative fixation for proximal tibia or tibial shaft fractures without preexisting ACS or neuromuscular/vascular conditions.
✕Probably not a fit
Patients with preoperative ACS, certain neuromuscular/vascular conditions, or those for whom the device malfunctions may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This trial tests whether continuous anterior leg compartment pressure monitoring in adolescents who undergo fixation of proximal tibia or tibial shaft fractures can distinguish those who develop acute compartment syndrome from those who do not. The device records pressure for about 18 hours after surgery to see if pressure patterns correlate with ACS diagnosis. The study is conducted at Boston Children's Hospital and involves patients aged 10–21, with specific exclusions to avoid those with preexisting conditions or device issues. Results could help determine if pressure monitoring improves ACS diagnosis after tibia fracture treatment.
Why it matters
Potential benefit: If successful, monitoring could help doctors detect ACS earlier and more accurately, potentially preventing complications.
How similar studies have gone: Previous studies with similar monitoring approaches have explored ACS detection, but this specific pediatric tibia fracture setting is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Between the ages of 10 to 21 on the day of surgery * Undergoing operative fixation for a fracture of the proximal tibia or tibial shaft Exclusion Criteria: * Preoperative diagnosis of acute compartment syndrome * Preexisting neuromuscular or vascular condition affecting the injured extremity * MY01 device malfunction
Where it's running
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Boston Children's Hospital
Boston, Massachusetts, United States Recruiting
Study contacts
- Principal investigator: Kristin Livingston, MD — Boston Children's Hospital
- Study coordinator: Kristin Livingston, MD
- Email: kristin.livingston@childrens.harvard.edu
- Phone: 617-355-6021
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Tissue ultrafiltration to prevent acute compartment syndrome after severe tibia fractures
This trial tests whether placing tissue ultrafiltration (TUF) catheters in adults 18–60 with severe proximal tibia or tibial shaft fractures can lower muscle pressure and prevent acute compartment syndrome compared with standard care.
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Research on Acute Compartment Syndrome after Femoropopliteal Arterial Injuries
This study looks at how often people develop Acute Compartment Syndrome after injuries to the femoropopliteal artery and what that means for their treatment and recovery.
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Research on Acute Compartment Syndrome
This study looks at how to better diagnose and treat acute compartment syndrome in adults with certain types of serious leg fractures to see if surgery is needed.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.