Comparison of Optrell and Octaray Mapping Catheters for Atrial Ablation

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective, single-center observational study compares two high-density multielectrode mapping catheters during catheter ablation for complex atrial arrhythmias. It evaluates real-time vector propagation and the ability to confirm conduction block across ablation lines without full chamber remapping, alongside a head-to-head comparison of bipolar voltage distributions from the two catheters. The study focuses on procedural workflow efficiency and key electrophysiological metrics to determine if Optrell offers similar or improved performance relative to Octaray. Eligible participants include adults with persistent AF or atrial flutter undergoing first-time or redo ablation with planned linear lesion sets. The investigation is conducted at Shamir Medical Center under the lead sponsor Maxime Zabern.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* • Age ≥18 years.
* • Documented persistent atrial fibrillation and/or atrial flutter.
* • Undergoing a clinically indicated first-time (de novo) or redo catheter ablation where linear ablation lesion sets (e.g., posterior wall, roof line, lateral mitral line, CTI) are planned or anticipated.
* • Ability to provide written informed consent.

Exclusion Criteria:

* • Paroxysmal or persistent AF where only standard PVI is planned.
* • Mechanical mitral valve.
* • Presence of intracardiac thrombus or contraindication to systemic anticoagulation.
* • Any medical condition or anatomical contraindication that, in the investigator's judgment, precludes safe participation.
* • Pregnant women.

Where it's running

• Shamir Medical Center
  Be’er Ya‘aqov, Israel Recruiting

Study contacts

• Principal investigator: Maxime Zabern, MD — Assaf-Harofeh Medical Center
• Study coordinator: Maxime Zabern, MD
• Email: maximz@shamir.gov.il
• Phone: +972-54-5644963

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.