Comparing two types of tendon grafts for knee ligament surgery

A Prospective Comparison of Clinical and Radiological Maturation Outcomes of Autologous Quadriceps and Hamstring Tendon Grafts in Anterior Cruciate Ligament Reconstruction

Not applicable Interventional Acibadem University · NCT06617559

This study is testing whether using hamstring or quadriceps tendon grafts for knee ligament surgery helps athletes recover better and perform well after an ACL injury.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment25 (estimated)
Ages18 Years and up
SexAll
SponsorAcibadem University Academic / other
Locations1 site (Istanbul)
Trial IDNCT06617559 on ClinicalTrials.gov

What this trial studies

This study aims to compare the clinical and radiological outcomes of anterior cruciate ligament (ACL) reconstruction using autologous hamstring tendon grafts versus quadriceps tendon grafts. With advancements in surgical techniques, the quadriceps tendon has gained attention for its potential benefits over traditional hamstring grafts. The study will involve elite and amateur athletes who have sustained ACL injuries, assessing their recovery and performance post-surgery. Participants will be monitored for complications and overall success of the grafts used in their reconstruction.

Who should consider this trial

Good fit: Ideal candidates for this study are elite and amateur athletes who have suffered an anterior cruciate ligament injury.

Not a fit: Patients who have undergone revision surgery or have other significant knee injuries may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide insights into which tendon graft offers better outcomes for ACL reconstruction, potentially improving recovery for athletes.

How similar studies have performed: Previous studies have shown promising results for quadriceps tendon grafts, suggesting that this approach may be a viable alternative to hamstring grafts.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Elite athletes
* Amateur athletes
* Anterior cruciate ligament injury

Exclusion Criteria:

* Revision surgery
* Another ligament injury ( medial collateral ligament, lateral collateral ligament, etc.. )
* \> Grade-2 cartilage injury
* Having previously undergone surgery on the same knee
* \< 18 years age

Where this trial is running

Istanbul

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Anterior Cruciate Ligament InjuriesAthletic InjuriesTendon GraftComplicationsanterior cruciate ligament reconstructionhamstring tendonsathletic injuries
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.