Comparing two types of nerve blocks for pain management after lumbar surgery

Comparison of the Effects of Thoracolumbar Interfascial Plane Block and Quadro Iliac Plane Block on Postoperative Opioid Consumption After Lumbar Microsurgery: A Randomized Controlled Trial

Not applicable Interventional Medipol University · NCT06851533

This study is testing two different nerve block techniques to see which one helps people have less pain and use fewer opioids after lumbar surgery.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment90 (estimated)
Ages18 Years to 80 Years
SexAll
SponsorMedipol University Academic / other
Locations1 site (Istanbul)
Trial IDNCT06851533 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of two regional anesthesia techniques, the Thoracolumbar Interfascial Plane (TLIP) block and the Quadro Iliac Plane Block, in reducing postoperative opioid use following lumbar microdiscectomy. The research aims to determine which method provides better pain control and fewer opioid-related side effects, such as nausea and respiratory depression. Patients aged 18 to 80 scheduled for this surgery will be included, and their postoperative pain levels will be assessed using a Numeric Rating Scale. The study seeks to enhance patient recovery by minimizing opioid consumption through effective pain management strategies.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 to 80 who are scheduled for lumbar microdiscectomy and have an ASA physical status of I to III.

Not a fit: Patients with known allergies to local anesthetics, significant drug allergies, or pre-existing psychiatric or neurological disorders may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management techniques that reduce reliance on opioids after lumbar surgery.

How similar studies have performed: While there is limited evidence directly comparing these two specific nerve block techniques, regional anesthesia has shown promise in improving postoperative pain management in similar contexts.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients aged 18 to 80 years
* American Society of Anesthesiologists (ASA) physical status I to III
* scheduled for lumbar microdiscectomy surgery

Exclusion Criteria:

* Known allergy to local anesthetics
* Any other significant drug allergies related to the study interventions
* Pregnancy
* Pre-existing psychiatric or neurological disorders
* Inability to provide informed consent

Where this trial is running

Istanbul

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Lumbar MicrodiscectomyNerve BlockPostoperative painUltrasound-guided nerve block
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.