Clinical trial Recruiting at 1 site Interventional Ages 18 to 80

Comparing two types of nerve blocks for pain management after lumbar surgery

Official title: Comparison of the Effects of Thoracolumbar Interfascial Plane Block and Quadro Iliac Plane Block on Postoperative Opioid Consumption After Lumbar Microsurgery: A Randomized Controlled Trial

Run by Medipol University · NCT06851533 · Data updated 2026-11-12

This study is testing two different nerve block techniques to see which one helps people have less pain and use fewer opioids after lumbar surgery.

More Nerve Block trials

Quick facts

Study typeInterventional
Ages18 Years to 80 Years
SexAll
Enrollment90 (estimated)
SponsorMedipol University
Academic / other
Locations1 site (Istanbul)
StatusRecruiting
StartedMarch 10, 2025
Main results expectedNovember 10, 2026
Study endsDecember 10, 2026
Registry record updatedJuly 27, 2026
Trial IDNCT06851533 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 to 80 who are scheduled for lumbar microdiscectomy and have an ASA physical status of I to III.

Probably not a fit

Patients with known allergies to local anesthetics, significant drug allergies, or pre-existing psychiatric or neurological disorders may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of two regional anesthesia techniques, the Thoracolumbar Interfascial Plane (TLIP) block and the Quadro Iliac Plane Block, in reducing postoperative opioid use following lumbar microdiscectomy. The research aims to determine which method provides better pain control and fewer opioid-related side effects, such as nausea and respiratory depression. Patients aged 18 to 80 scheduled for this surgery will be included, and their postoperative pain levels will be assessed using a Numeric Rating Scale. The study seeks to enhance patient recovery by minimizing opioid consumption through effective pain management strategies.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management techniques that reduce reliance on opioids after lumbar surgery.

How similar studies have gone: While there is limited evidence directly comparing these two specific nerve block techniques, regional anesthesia has shown promise in improving postoperative pain management in similar contexts.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients aged 18 to 80 years
* American Society of Anesthesiologists (ASA) physical status I to III
* scheduled for lumbar microdiscectomy surgery

Exclusion Criteria:

* Known allergy to local anesthetics
* Any other significant drug allergies related to the study interventions
* Pregnancy
* Pre-existing psychiatric or neurological disorders
* Inability to provide informed consent

Where it's running

  • Medipol University
    Istanbul, Turkey (Türkiye)
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.