Comparing two types of nerve blocks for knee surgery
Official title: Subsartorial Saphenous Nerve Block (SSNB) Versus Femoral Nerve Block (FNB) in Primary Total Knee Arthroplasty (TKA) Combined With Infiltration Between Popliteal Artery and Capsule of the Knee (IPACK) - Where Are the Benefits?
Run by Luzerner Kantonsspital · NCT06074744 · Data updated 2026-11-12
This study is testing which type of nerve block works better for pain control and recovery in people having knee surgery.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 144 (estimated) |
| Sponsor | Luzerner Kantonsspital Academic / other |
| Locations | 1 site (Lucerne) |
| Status | Recruiting |
| Started | November 30, 2023 |
| Main results expected | December 2026 |
| Study ends | December 2026 |
| Registry record updated | March 12, 2024 |
| Trial ID | NCT06074744 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults over 18 years old who are scheduled for primary Total Knee Arthroplasty and have a BMI of 35 kg/m² or less.
✕Probably not a fit
Patients who may not benefit from this study include those under 18 years old, those undergoing revision TKA, or those with significant comorbidities that contraindicate the interventions.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial aims to compare the effectiveness of Subsartorial Saphenous Nerve Block (SSNB) combined with IPACK against Femoral Nerve Block (FNB) with IPACK in patients undergoing primary Total Knee Arthroplasty (TKA). Participants will be randomly assigned to one of the two groups, and the study will assess various outcomes including muscle power output, pain control, mobility, and patient satisfaction. The trial is designed as a prospective, randomized, double-blinded, single-center study with a total of 144 participants. The nerve blocks will be administered by trained anesthesiologists, and the surgical procedure will follow standard protocols.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management and functional recovery for patients undergoing knee surgery.
How similar studies have gone: Other studies have shown promising results with similar nerve block techniques, suggesting potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion criteria: * age \> 18yrs * primary TKA * BMI 35kg/m2 or less * able to give informed consent as documented by signature * clinical history without any contraindications for the planned intervention Exclusion criteria: * age \< 18 years * revision-TKA * BMI \>35kg/m2 * absent contact information * inability or contraindications to undergo the investigated intervention (TKA, FNB, SSNB), - clinically significant concomitant diseases * pregnancy * inability to follow the procedures and follow-up procedures of the study (e.g. due to language problems, psychological disorders, dementia, living abroad, etc. * withdrawal from the study
Where it's running
-
Luzerner Kantonsspital
Lucerne, Switzerland Recruiting
Study contacts
- Principal investigator: Judith Bering, Dr. med. — Luzerner Kantonsspital Luzern
- Study coordinator: Judith Bering, Dr. med.
- Email: judith.bering@luks.ch
- Phone: +41 41 205 18 91
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.