Comparing two types of grafts for knee ligament surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates the effectiveness of two different grafts used in Anterior Cruciate Ligament (ACL) reconstruction: the semitendinosus hamstrings graft and the quadriceps tendon graft. Conducted at Capio Artro Clinic in Stockholm, the study involves a randomized control design with 200 athletes who have sustained ACL injuries. Participants will be monitored over a two-year period to assess outcomes such as knee laxity, return to sports, and graft maturity through MRI scans. The study aims to provide insights into which graft may offer better long-term results for athletes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Pre-injury Tegner Activity Scale≥7
* Intended return to sports to prior sport and Tegner Activity Scale Level
* Time between injury and inclusion not more than 6 months
* MR verified ACL rupture

Exclusion Criteria:

* Previous knee injury with symptoms before ACL injury
* Neurological disease, inflammatory disease, connective tissue disease or balance disorder
* Previous lower limb fracture or surgery
* Laxity in the medial collateral ligament (MCL) and lateral collateral ligament (LCL) \> grade 1
* PCL rupture or Multiligament knee injury (MLKI)
* Radiographic sign of osteoarthritis (OA)
* Previous knee surgery or ligament injury in contralateral knee
* Beighton score ≥ 5

Where it's running

• Capio Artro Clinic AB
  Stockholm, Stockholm County, Sweden Recruiting

Study contacts

• Principal investigator: Anders Stålman, MD,PhD — Karolinska Institutet
• Study coordinator: Anders Stålman, MD,Phd
• Email: anders.stalman@ki.se
• Phone: 0046736665957

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.