Comparing two types of cognitive-behavioral therapy for anxiety disorders
Transdiagnostic Versus Diagnosis-specific Cognitive-behavioral Therapy for Anxiety Disorders: a Randomized Controlled Pilot Study
This study is testing whether a new type of cognitive-behavioral therapy can help people with different anxiety disorders feel better compared to a more traditional approach.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 76 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | Karolinska Institutet Academic / other |
| Locations | 1 site (Stockholm) |
| Trial ID | NCT05249543 on ClinicalTrials.gov |
What this trial studies
This pilot study aims to assess the feasibility of conducting a randomized controlled trial comparing transdiagnostic cognitive-behavioral therapy (CBT) using the unified protocol with diagnosis-specific CBT for patients suffering from various anxiety disorders. The study will evaluate participant recruitment, retention, therapist competence, treatment adherence, and patient satisfaction in routine psychiatric outpatient care in Stockholm, Sweden. Additionally, it will explore the clinical effects of both treatment approaches on anxiety severity, depressive symptoms, and overall quality of life.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18-65 with a principal diagnosis of panic disorder, generalized anxiety disorder, social anxiety disorder, obsessive-compulsive disorder, or posttraumatic stress disorder.
Not a fit: Patients with current psychotic disorders, bipolar disorder, severe substance use disorders, or those at moderate to severe risk of suicide may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into more effective treatment options for patients with anxiety disorders.
How similar studies have performed: Previous studies have shown success in comparing transdiagnostic and diagnosis-specific approaches, indicating potential for meaningful insights in this area.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18-65 years of age, * Being able to speak Swedish without interpreter support, * A principal diagnosis of panic disorder, generalized anxiety disorder, social anxiety disorder, obsessive-compulsive disorder, or posttraumatic stress disorder, and * Pharmacological treatment (if any) that is stable six weeks prior to treatment start Exclusion Criteria: * Current diagnosis of psychotic disorder, bipolar disorder, or moderate to severe substance use disorder, * Moderate to severe risk of suicide, * Psychiatric, somatic, or social problems which require other management or intervention than cognitive-behavioral therapy, and * Other simultaneous psychological treatment
Where this trial is running
Stockholm
- WeMind — Stockholm, Sweden (Recruiting)
Study contacts
- Principal investigator: Benjamin Bohman, PhD — Karolinska Institutet
- Study coordinator: Benjamin Bohman, PhD
- Email: benjamin.bohman@ki.se
- Phone: 701713443
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.