Comparing two treatments for prostate issues

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial is a randomized controlled trial designed to compare the effectiveness of two treatments for benign prostatic hyperplasia (BPH): water vapor thermal treatment (REZUM) and prostatic urethral lift (UroLift). Participants will be randomly assigned to one of the two treatment arms in a 1:1 ratio. The study aims to determine if REZUM is non-inferior to UroLift in alleviating symptoms associated with BPH. The trial will focus on male patients aged 50 and older who have a specific range of prostate volume and symptom severity.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Male ≥ 50 years Symptomatic BPH International prostate symptom score (IPSS) ≥13 Prostate volume 30-80ml

Exclusion Criteria:

* History or high suspicion of prostate cancer
* Current urinary tract infection
* Refractory urinary retention or post-void residual (PVR) ≥250 mL
* Intravesical prostatic protrusion (IPP)\>10mm
* Prior prostate surgery
* Known or suspected allergy to nickel, titanium, or polyester/polypropylene
* Urethral stricture, meatal stenosis, bladder neck contracture
* Neurogenic bladder and/or sphincter abnormalities

Where it's running

• Prince of Wales Hospital, The Chinese University of Hong Kong
  Hong Kong, Hong Kong Recruiting

Study contacts

• Study coordinator: Peter Ka-Fung CHIU
• Email: peterchiu@surgery.cuhk.edu.hk
• Phone: +852 3505 2625

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Tamsulosin With or Without Tadalafil for a Trial Without Catheter After Acute Urinary Retention

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• Tamsulosin dose change or switch to silodosin before catheter removal in men with BPH-related acute urinary retention

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  Recruiting Phase 4 Beni-Suef University · Banī Suwayf, Beni Suweif Governorate · NCT07650968

• Water Vapor Therapy vs Ejaculation-Sparing Enucleation for Benign Prostatic Hyperplasia

  This study tests whether Water Vapor Thermal Therapy (Rezum) or an ejaculation-sparing enucleation procedure better helps sexually active men with bothersome BPH symptoms.

  Recruiting Beni-Suef University · Banī Suwayf, Beni Suweif Governorate · NCT07648888

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.