Comparing two surgical options for reconstructing the bowel after colectomy in ulcerative colitis patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the two primary reconstructive surgical options available for patients with ulcerative colitis who have undergone colectomy: ileal pouch anal anastomosis (IPAA) and ileorectal anastomosis (IRA). Patients eligible for both procedures will receive standardized information and then choose their preferred surgical method. The study aims to assess patient satisfaction, quality of life, functional outcomes, and complications associated with each reconstructive approach. It is a prospective, non-randomized, multi-center, controlled trial that will also include a control group of patients who do not opt for reconstruction.

Why it matters

Who can join: the full rules

Inclusion criteria:

* Patients with Ulcerative colitis (UC) aged between 18 and 60
* Scheduled for or have previously undergone subtotal colectomy and ileostomy.
* Patients should have sufficient rectal compliance and controllable inflammation in the rectal using topical Mezalasin only.

Exclusion criteria

* Rectal inflammation of Mayo Score \>1
* Poor sphincter function, perianal disease
* Uncertainty regarding UC diagnosis P
* Previous colorectal cancer or severe dysplasia
* Primary Sclerosing Colitis diagnosis
* \>2 year since subtotal colectomy

Where it's running

• Sahlgrenska Univercity Hospital
  Gothenburg, Sweden Recruiting
• Linkoeping University hospital
  Linköping, Sweden Recruiting
• Karolinska University Hospital
  Solna, Sweden Recruiting
• St. Mark's Hospital
  London, United Kingdom Recruiting

Study contacts

• Study coordinator: Anton Risto
• Email: anton.risto@liu.se
• Phone: 0702510374

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.