Comparing two surgical methods for treating prostate enlargement while preserving ejaculation

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to compare the effectiveness of partial transurethral resection of the prostate with conventional transurethral resection for men suffering from benign prostatic hyperplasia. It focuses on improving lower urinary tract symptoms and preserving ejaculatory function, which is often compromised by traditional surgical methods. The trial employs a multicenter randomized design with single-blinded patients, assessing outcomes at six months post-surgery. Key measures include urinary flow, sexual life quality, and complication rates.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Man over 40 years old
* Indication of surgical management for BPH
* Prostate volume ≥30 cc and ≤150 cc as evaluated by ultrasonography ( or an MRI if available)
* IPSS score ≥12
* Qmax ≤15 ml/s
* Affiliated to French national social security system
* wish and be able to comply with planned visits
* Able to express his consent
* Signed informed consent form

Exclusion Criteria:

* Unwillingness to accept the treatment
* No pre-operative ejaculation or sexuality
* Neurological pathology responsible for micturition disorders
* History of prostatic surgery
* Stenosis of the urethra symptomatic
* History of prostate cancer
* History of radiotherapy or pelvic surgery
* Patient refusing the principle of partial surgery
* Life expectancy \<3 years
* Inability to understand the informed consent document, to give consent voluntarily or to complete the study tasks.
* Participation in another clinical study involving an investigational product within 1 month before study entry.

Where it's running

• CH Pays d'Aix
  Aix-en-Provence, France Recruiting
• CHU Angers
  Angers, France Recruiting
• Centre Hospitalier Universitaire de Bordeaux
  Bordeaux, France Recruiting
• CHU de Limoges
  Limoges, France Recruiting
• Hôpital Nord Marseille
  Marseille, France Recruiting
• Polyclinique Saint George
  Nice, France Recruiting

Study contacts

• Study coordinator: Grégoire ROBERT
• Email: gregoire.robert@chu-bordeaux.fr
• Phone: 05.57.82.06.87

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.