Comparing two methods for treating stroke caused by basilar artery blockage

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to compare the effectiveness of two thrombectomy techniques—contact aspiration and stent retriever thrombectomy—in patients suffering from acute ischemic stroke due to basilar artery occlusion. The study will enroll adults who meet specific criteria and will assess the speed and success of recanalization, which is crucial for improving patient outcomes. The trial is designed to provide insights into which method may lead to better recovery rates and overall prognosis for these patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Age ≥ 18 years

* AIS with BAO on non-invasive imaging (CT or MRI)
* Eligible for thrombectomy : groin puncture undergone within 24 hours of first symptoms or of last time the patient was seen normal
* Being covered by a national health insurance
* Informed consent obtained from the patients/his proxy or following an emergency procedure

Exclusion Criteria:

* Known or suspected pre-existing (chronic) large vessel stenosis / occlusion in the symptomatic territory (basilar artery)
* Severe contrast medium allergy or absolute contraindication to use of iodinated products
* Clinical history, past imaging or clinical judgment suggesting intracranial stenosis of the basilar artery
* Pregnancy (urine or serum beta HCG test for women of child-bearing potential)
* Person deprived of liberty
* Patient benefiting from a legal protection (guardianship or curatorship)

Where it's running

• Chu Bordeaux
  Bordeaux, France Recruiting
• Chru Nancy
  Nancy, France Recruiting
• Fondation Adolphe de Rothschild
  Paris, France Recruiting
• Hôpital FOCH
  Suresnes, France Recruiting
• CHU Caen
  Caen, France Not yet recruiting
• CHU Limoges
  Limoges, France Not yet recruiting

Study contacts

• Principal investigator: Arturo CONSOLI — Study principal investigator
• Study coordinator: Arturo CONSOLI
• Email: a.consoli@hopital-foch.com
• Phone: 0033146251955

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Endovascular Therapy for Basilar Artery Occlusion With Large Ischemic Core

  This trial tests whether adding endovascular therapy to standard medical care helps people with acute basilar artery occlusion and a large area of brain already affected.

  Recruiting The First Affiliated Hospital of University of Science and Technology of China · Hefei, Anhui · NCT07672795

• Basilar artery occlusion with large brain infarct: real-world endovascular vs medical therapy

  This registry follows adults with basilar artery occlusion and a large core infarct to see how endovascular therapy compares to medical management in routine care.

  Recruiting Xuanwu Hospital, Beijing · Beijing, Beijing Municipality · NCT07345702

• Tenecteplase before transfer for basilar artery stroke 4.5–24 hours after symptom onset

  This trial tests whether giving IV tenecteplase before transfer helps people with basilar artery occlusion who are 4.5–24 hours from symptom onset and are being sent for thrombectomy.

  Recruiting Phase 4 Xuanwu Hospital, Beijing · Beijing · NCT07203625

• Endovascular treatment for acute basilar artery stroke with a large infarct core

  This trial will test whether adding endovascular clot removal to standard medical care helps adults with acute basilar artery occlusion who already have a large area of brain damage.

  Recruiting at 2 sites The First Affiliated Hospital of Hainan Medical University · Hefei, Anhui and 1 other locations · NCT07090941

• Rescue treatment for mild ischemic stroke with basilar artery blockage

  This study is testing if combining a new type of treatment with standard care can help people with mild strokes caused by a blocked basilar artery feel better and recover more effectively.

  Recruiting at 2 sites First Affiliated Hospital of Wannan Medical College · Hefei, Anhui and 1 other locations · NCT06843356

• Extending treatment options for stroke caused by basilar artery blockage

  This study is testing if a new treatment called tenecteplase can help people who have had a stroke from a blocked basilar artery feel better and recover more effectively compared to standard care.

  Recruiting at 13 sites Phase 2/3 University of Melbourne · Bankstown, New South Wales and 16 other locations · NCT05105633

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.