Comparing two methods for fixing dentures in edentulous jaws

Marginal Bone Changes in Fixed All-on-Four Mandibular Prosthesis Using OT Bridge Attachment System Versus Conventionally Screw Retained Multiunit Abutments: A Randomized Clinical Trial

Not applicable Interventional Cairo University · NCT05924386

This study is testing whether a new way to attach dentures can help people without teeth keep their jawbone healthy better than the traditional method.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment20 (estimated)
Ages40 Years and up
SexAll
SponsorCairo University Academic / other
Locations2 sites (Cairo and 1 other locations)
Trial IDNCT05924386 on ClinicalTrials.gov

What this trial studies

This clinical trial investigates the marginal bone changes in edentulous patients receiving fixed mandibular prostheses using two different attachment systems: conventional screw retained multiunit abutments and the OT bridge attachment system. Patients will be divided into two groups, with both undergoing implant placement guided by a surgical template. The study aims to assess the effectiveness of the OT bridge attachment system compared to traditional methods in maintaining bone integrity around the implants. Participants will be monitored over a healing period of eight to twelve weeks post-implant placement.

Who should consider this trial

Good fit: Ideal candidates are edentulous individuals aged 40 years or older with sufficient bone height and diameter for implant placement.

Not a fit: Patients with general contraindications for oral surgery, heavy smokers, or those with uncontrolled diabetes may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve the stability and longevity of dental implants for edentulous patients.

How similar studies have performed: Previous studies have shown promising results with similar implant attachment systems, suggesting potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

Patients with completely edentulous patients

* Aged 40 years or older.
* Sufficient inter -arch space not less than 13 mm.
* Good oral hygiene
* Minimum bone height 10 mm and minimum bone diameter should be 6 mm

Exclusion Criteria:

* General contraindications for oral surgery
* Heavy smokers (greater than 20 cigarettes a
* Local acute or chronic infections
* Substance abuse (drugs or alcohol)
* Patients with neuromuscular or psychiatric disorders.
* Treatment with intravenous bisphosphonates
* Irradiation of the neck or head area in the past 5 years
* Diabetic patients (HbA1c\>7.5%)

Where this trial is running

Cairo and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Edentulous JawOTbridge attachmentALL ON 4fixed supported implant prosthesisconventional screw retained fixed prosthesis
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.