Immediate short implants to replace a single extracted tooth
Primary Stability and Peri-implant Outcomes of Short Implants in Post-extraction Single-tooth Sites: a Randomized Controlled Trial.
NA · University of Bari Aldo Moro · NCT07177521
This study will test whether placing short dental implants right after removing a single tooth in patients with limited bone provides solid support and healthy gum and bone healing.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 10 (estimated) |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Sponsor | University of Bari Aldo Moro (other) |
| Locations | 1 site (Bari) |
| Trial ID | NCT07177521 on ClinicalTrials.gov |
What this trial studies
Participants who need a single-tooth replacement following extraction (primarily premolars and molars, and some selected anterior sites) will receive a short implant (about 7–8 mm or shorter) placed immediately into the extraction socket. The trial will focus on how the peri-implant gap and soft-tissue management affect primary implant stability and subsequent hard- and soft-tissue remodeling. Clinical measurements and radiographs will be used during follow-up visits to monitor stability, tissue changes, and implant survival. Patients with significant bone defects or contraindications to healing will be excluded to preserve primary stability and standardize results.
Who should consider this trial
Good fit: Adults (≥18) needing immediate single-tooth replacement in posterior sites or selected anterior sites, with good oral hygiene and a planned short implant (≤7–8 mm), are ideal candidates.
Not a fit: Patients who are heavy smokers (>20 cigarettes/day), have uncontrolled diabetes or conditions that impair bone healing, are on antiresorptive therapy, are immunosuppressed or pregnant, have poor oral hygiene or acute site infection, or have severe bone dehiscence are unlikely to benefit.
Why it matters
Potential benefit: If successful, this approach could offer a faster, less invasive option for replacing a single tooth when vertical bone height is limited.
How similar studies have performed: Previous clinical reports on immediate placement and on short implants have shown promising results in well-selected patients, though outcomes depend strongly on case selection and soft-tissue/bone management.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥18 years. * Single-tooth post-extraction sites requiring immediate implant placement in posterior regions (premolars/molars) or selected anterior sites. * Planned short implant (≤7-8 mm length, 3.5-5.0 mm diameter). * Adequate oral hygiene, no active periodontal disease. * Written informed consent. Exclusion Criteria: * Heavy smoking (\>20 cigarettes/day). * Uncontrolled diabetes or systemic conditions affecting bone healing. * Current bisphosphonate/antiresorptive therapy. * Immunosuppression, pregnancy. * Poor oral hygiene or acute infection at site. * Severe bone dehiscence preventing primary stability.
Where this trial is running
Bari
- University of Bari Aldo Moro — Bari, Italy (RECRUITING)
Study contacts
- Principal investigator: Giuseppe D'Albis, Dr — University of Bari Aldo Moro
- Study coordinator: Giuseppe D'Albis, Dr
- Email: giuseppe.dalbis@uniba.it
- Phone: +393495103642
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Edentulous Jaw, Tooth Loss, Toothless Mouth