Comparing two methods for correcting astigmatism during cataract surgery

Femtosecond Laser Arcuate Keratotomy Versus Toric Intraocular Lens Implantation in Cataract Surgery

NA · Second Affiliated Hospital, School of Medicine, Zhejiang University · NCT06215807

This study is testing whether a special laser treatment or a specific type of lens works better to fix astigmatism in patients having cataract surgery.

Quick facts

PhaseNA
Study typeInterventional
Enrollment200 (estimated)
Ages18 Years to 80 Years
SexAll
SponsorSecond Affiliated Hospital, School of Medicine, Zhejiang University (other)
Locations1 site (Hangzhou, Zhejiang)
Trial IDNCT06215807 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the effectiveness of femtosecond laser arcuate keratotomy versus Toric intraocular lens implantation for correcting astigmatism in patients undergoing femtosecond laser-assisted cataract surgery. Patients with regular corneal astigmatism between 0.75 and 3.00 D will be randomly assigned to receive one of the two interventions in each eye. The study will assess visual acuity, subjective manifest refraction, and corneal topography over the long term to determine which method provides better outcomes. This prospective randomized comparative approach seeks to enhance patient satisfaction and visual quality post-surgery.

Who should consider this trial

Good fit: Ideal candidates are cataract patients with binocular regular corneal astigmatism ranging from 0.75 to 3.00 D who are planning to undergo femtosecond laser-assisted cataract surgery.

Not a fit: Patients with irregular corneal astigmatism, ocular surface abnormalities, or other significant ocular or systemic conditions may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved visual outcomes and higher satisfaction for cataract patients with astigmatism.

How similar studies have performed: Other studies have explored similar approaches for astigmatism correction, indicating potential for success, though this specific comparison may be novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* cataract patients
* patients with binocular regular corneal astigmatism ranging from 0.75 to 3.00 D
* patients who plan to receive femtosecond laser-assisted cataract surgery

Exclusion Criteria:

* patients with ocular surface abnormalities such as irregular corneal astigmatism, corneal scarring, keratoconus, and pterygium)
* patients with history of ocular trauma or surgery
* patients with coexisting ocular disorders such as glaucoma, retinal vascular occlusive disease, retinal detachment, diabetic retinopathy, and any optic nerve-related pathologies
* patients with concurrent severe systemic diseases
* patients who lack of cooperation

Where this trial is running

Hangzhou, Zhejiang

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Cataract, Astigmatism, Astigmatism correction, Femtosecond laser arcuate keratotomy, Toric intraocular lens implantation, Femtosecond laser-assisted cataract surgery

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.