Comparing two knee replacement techniques for better outcomes

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effectiveness of two different surgical techniques for total knee arthroplasty: mechanical alignment and restricted kinematic alignment. Mechanical alignment aims for a straight knee to enhance implant longevity, while restricted kinematic alignment customizes the knee replacement to fit each patient's unique anatomy. The study will assess patient satisfaction, functional outcomes, and knee motion to determine which approach yields better results. By utilizing robotic-assisted surgery, the trial aims to provide more personalized treatment options for patients with knee osteoarthritis.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult aged 18 years or older
* Knee osteoarthritis requiring total knee arthroplasty
* Provide informed consent

Exclusion Criteria:

* Inability to provide informed consent (e.g. cognitive disability, language barrier)
* Revision knee surgery
* Simultaneous bilateral knee surgery
* Recent lower extremity surgery or trauma interfering with gait assessment
* A CT scan cannot be obtained prior to surgery
* Inability or unwillingness to comply with the study protocol

Where it's running

• St. Joseph's Healthcare
  Hamilton, Ontario, Canada Recruiting

Study contacts

• Study coordinator: Kim Madden, PhD
• Email: maddenk@mcmaster.ca
• Phone: 289-237-7380

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Mind mapping-based education to help after knee replacement

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• DoACs vs LMWH for blood flow after knee replacement

  This study tests whether rivaroxaban, apixaban, or LMWH work differently to support blood flow in the legs after total knee replacement in adults.

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• Early wear of a Vitamin E-infused liner in a dual-mobility hip replacement

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  Recruiting Phase 4 Uppsala University · Uppsala, Uppsala County · NCT07863557

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.