Comparing treatments for oral mucositis in children undergoing chemotherapy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the effectiveness of sodium bicarbonate, saline, and black mulberry syrup in reducing oral mucositis in children aged 6-18 years receiving chemotherapy. Participants will be randomly assigned to one of three groups: the control group will receive standard sodium bicarbonate treatment, while the intervention groups will receive either saline or black mulberry syrup in addition to the standard care. Oral care will be administered four times daily for 14 days, and the severity of mucositis will be assessed using established scales and neutrophil counts at multiple time points. The goal is to determine which treatment is most effective in alleviating the symptoms of oral mucositis.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* The willingness of the family and the child to participate in the study
* Parent and child have separately informed written consent form
* Be between 6-18 years old
* Receiving chemotherapy and being hospitalized for chemotherapy treatment
* Being fed orally

Exclusion Criteria:

* Oral mucositis in the first intraoral evaluation
* Having diabetes
* Receiving radiotherapy
* Having a surgical procedure in the mouth and jaw area
* Receiving steroid therapy during chemotherapy treatment
* Using a method other than the methods used in the study to protect the oral mucous membrane throughout the study

Where it's running

• Isparta City Hospital
  Isparta, Turkey (Türkiye) Recruiting

Study contacts

• Principal investigator: Selda Ateş Beşirik, Assistant Professor — Burdur Mehmet Akif Ersoy University
• Study coordinator: Selda Ateş Beşirik, Assistant Professor
• Email: seldaates07@gmail.com
• Phone: +905543683323

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.