Comparing treatment options for mid-low rectal cancer

Choice of the Optimal Treatment Strategies for Mid-low REctal Cancer-a National Multi-center, Prospective, Real World Study

Observational Peking Union Medical College Hospital · NCT05871762

This study is testing different treatment options for mid-low rectal cancer to see which ones work best and are most cost-effective for patients and healthcare providers in China.

Quick facts

Study typeObservational
Enrollment3705 (estimated)
SexAll
SponsorPeking Union Medical College Hospital Academic / other
Locations1 site (Beijing, Beijing Municipality)
Trial IDNCT05871762 on ClinicalTrials.gov

What this trial studies

This observational study aims to evaluate the efficacy, prognosis, and health economics of various treatment modalities for mid-low rectal cancer across different centers in China. It will conduct a cost utility analysis to identify the most effective treatment strategies that align with the needs of medical units at various levels. The findings are expected to inform evidence-based medical guidelines and improve decision-making in medical management and insurance for rectal cancer.

Who should consider this trial

Good fit: Ideal candidates include individuals with pathologically confirmed rectal adenocarcinoma located within 12cm of the anal verge.

Not a fit: Patients with distant metastasis, multiple primary colorectal cancers, a history of previous malignant tumors, or who are pregnant or lactating may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to optimized treatment strategies for mid-low rectal cancer, improving patient outcomes and resource allocation.

How similar studies have performed: Other studies have shown success in evaluating treatment strategies for rectal cancer, but this specific approach focusing on cost utility analysis is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* pathologically confirmed rectal adenocarcinoma
* located within 12cm below the anal verge

Exclusion Criteria:

* diagnosed with distant metastasis
* multiple primary colorectal cancers
* history of previous malignant tumors
* Pregnant or lactating women

Where this trial is running

Beijing, Beijing Municipality

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Rectal Neoplasms
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.