Comparing surgical methods for metastatic pathologic fractures
Official title: Metastatic Pathologic Fractures: Short Term Results of Endoprosthetic Reconstruction, Intramedullary Nail and Open Reduction Internal Fixation
Run by Ankara University · NCT05825456 · Data updated 2026-11-12
This study is testing which of three surgical methods works best to help people with painful fractures caused by cancer so they can feel better and move around more easily.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 200 (estimated) |
| Sponsor | Ankara University Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Ankara, altindag) |
| Status | Recruiting |
| Started | January 1, 2022 |
| Main results expected | January 1, 2026 |
| Study ends | January 1, 2026 |
| Registry record updated | March 5, 2025 |
| Trial ID | NCT05825456 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include patients with metastatic pathologic fractures who are undergoing surgical intervention.
✕Probably not a fit
Patients with primary bone tumors or those managed conservatively will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to evaluate the short-term outcomes of three surgical interventions—endoprosthetic reconstruction, intramedullary nailing, and open reduction internal fixation—for patients with metastatic pathologic fractures. Conducted at Ankara University, the study will assess factors such as the primary tumor type, chemotherapy and radiotherapy history, and various risk scores to determine the most effective surgical approach. The goal is to relieve pain and facilitate early mobilization in patients suffering from these fractures, which often require surgical intervention rather than conservative treatment.
Why it matters
Potential benefit: If successful, this study could improve surgical outcomes and quality of life for patients with metastatic pathologic fractures.
How similar studies have gone: While there have been studies on surgical interventions for metastatic fractures, this specific comparative approach is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * metastatic pathologic fracture * operated via endoprosthesis, intramedullary nail or plate \& screws Exclusion Criteria: * primary bone tumor * conservative management * neuromuscular disease * periprosthetic fractures * less than 1 month follow up
Where it's running
-
Ankara University Medical Faculty
Ankara, altindag, Turkey (Türkiye) Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.