Comparing staining techniques for detecting dysplasia in colitis patients
A Prospective Trial Comparing Chromoendoscopy to a Digital Staining Technique and White Light in High Definition Colonoscopy in Patients With IBD Attending Scheduled Surveillance Colonoscopy
This study is testing different imaging methods during colonoscopy to see which one is best at finding early signs of dysplasia in patients with inflammatory bowel disease.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 106 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Vastra Gotaland Region Government |
| Locations | 1 site (Gothenburg, Molndal) |
| Trial ID | NCT06223347 on ClinicalTrials.gov |
What this trial studies
This study compares different imaging techniques, including chromoendoscopy, white light imaging (WLI), narrow band imaging (NBI), and texture and color enhancement imaging (TXI), to determine the most effective method for diagnosing dysplasia in patients with inflammatory bowel disease (IBD) during scheduled surveillance colonoscopy. Utilizing high-definition colonoscopy, the study aims to identify the simplest and most efficient approach for dysplasia detection. By evaluating these techniques against each other, the research seeks to improve diagnostic accuracy and patient outcomes.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals scheduled for surveillance colonoscopy due to inflammatory bowel disease.
Not a fit: Patients who have undergone total colectomy or have poorly prepared bowels will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more accurate and easier detection of dysplasia in colitis patients, potentially improving surveillance and treatment outcomes.
How similar studies have performed: Other studies have shown promise in using advanced imaging techniques for dysplasia detection, but this specific comparison of methods is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: - Person schedules to IBD- surveillance colonoscopy. Exclusion Criteria: * Total Colectomy. * Not well prepared Bowel. BBPS under 2 at any segement. * Pregnancy.
Where this trial is running
Gothenburg, Molndal
- Sahlgrenska University Hospital — Gothenburg, Molndal, Sweden (Recruiting)
Study contacts
- Study coordinator: Naz Mohammed Salih, Dr.
- Email: naz.mohammed.salih@vgregion.se
- Phone: +46720267227
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.