Comparing spinal and general anesthesia for hip fracture surgery
Spinal Versus General Anesthesia on Postoperative Pulmonary Complications in Elderly Patients With Delayed Operation of Hip Fracture
NA · Tongji Hospital · NCT06425627
This study tests whether spinal anesthesia or general anesthesia leads to better breathing results after hip surgery in older patients who had to wait more than two days for their operation.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 40 (estimated) |
| Ages | 65 Years and up |
| Sex | All |
| Sponsor | Tongji Hospital (other) |
| Locations | 1 site (Wuhan, Hubei) |
| Trial ID | NCT06425627 on ClinicalTrials.gov |
What this trial studies
This study investigates the differences in postoperative pulmonary complications between spinal anesthesia and general anesthesia in patients aged 65 and older undergoing delayed hip surgery. The main outcome measure is the arterial partial pressure of oxygen 30 minutes after surgery, assessed through pulmonary ultrasound and other monitoring techniques. The study focuses on patients who have experienced a delay of more than 48 hours from diagnosis to surgery for hip fractures. By comparing these two anesthesia methods, the study aims to determine which approach may lead to better respiratory outcomes post-surgery.
Who should consider this trial
Good fit: Ideal candidates are patients aged 65 and older with specific types of hip fractures who have experienced a delay of more than 48 hours before surgery.
Not a fit: Patients who are unable to walk without assistance, require emergency surgery, or have significant comorbidities may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could help identify the anesthesia method that minimizes postoperative pulmonary complications in elderly patients undergoing hip surgery.
How similar studies have performed: Previous studies have explored anesthesia methods in surgical settings, but this specific comparison in the context of delayed hip surgery is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients ≥ 65 years old * ASA Class I \~ III * Surgical repair of femoral neck, intertrochanteric or subtrochanteric fractures * The time from diagnosis to surgery is more than 48 hours Exclusion Criteria: * Unable to walk about 3 meters or across a room without assistance before the fracture * Emergency surgery * Congestive heart failure, asthma, anemia (Hb \< 90 g/L), hypoalbuminemia (ALB \< 35g/L) * Abnormal coagulation function * Severe aortic stenosis * Injection site infection or increased intracranial pressure * Patients have participated in previous trials or have been determined by a surgeon or anesthesiologist to be unsuitable for randomization * The written informed consent of the patient or his/her representative cannot be obtained
Where this trial is running
Wuhan, Hubei
- Tianzhu Liu — Wuhan, Hubei, China (RECRUITING)
Study contacts
- Principal investigator: Tianzhu Liu, M.D. — Tongji Hospital
- Study coordinator: Tianzhu Liu, M.D.
- Email: liutzh@126.com
- Phone: 13098866448
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Pulmonary Complication, Anesthesia, Hip Fractures, Hip fracture, delayed surgery, pulmonary complication, spinal anesthesia, general anesthesia