Comparing spinal and general anesthesia for hip fracture surgery
Official title: Spinal Versus General Anesthesia on Postoperative Pulmonary Complications in Elderly Patients With Delayed Operation of Hip Fracture
Run by Tongji Hospital · NCT06425627 · Data updated 2026-11-12
This study tests whether spinal anesthesia or general anesthesia leads to better breathing results after hip surgery in older patients who had to wait more than two days for their operation.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 65 Years and up |
| Sex | All |
| Enrollment | 40 (estimated) |
| Sponsor | Tongji Hospital Academic / other |
| Locations | 1 site (Wuhan, Hubei) |
| Status | Recruiting |
| Started | June 12, 2024 |
| Main results expected | May 20, 2026 |
| Study ends | May 20, 2026 |
| Registry record updated | September 17, 2025 |
| Trial ID | NCT06425627 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are patients aged 65 and older with specific types of hip fractures who have experienced a delay of more than 48 hours before surgery.
✕Probably not a fit
Patients who are unable to walk without assistance, require emergency surgery, or have significant comorbidities may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the differences in postoperative pulmonary complications between spinal anesthesia and general anesthesia in patients aged 65 and older undergoing delayed hip surgery. The main outcome measure is the arterial partial pressure of oxygen 30 minutes after surgery, assessed through pulmonary ultrasound and other monitoring techniques. The study focuses on patients who have experienced a delay of more than 48 hours from diagnosis to surgery for hip fractures. By comparing these two anesthesia methods, the study aims to determine which approach may lead to better respiratory outcomes post-surgery.
Why it matters
Potential benefit: If successful, this study could help identify the anesthesia method that minimizes postoperative pulmonary complications in elderly patients undergoing hip surgery.
How similar studies have gone: Previous studies have explored anesthesia methods in surgical settings, but this specific comparison in the context of delayed hip surgery is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients ≥ 65 years old * ASA Class I \~ III * Surgical repair of femoral neck, intertrochanteric or subtrochanteric fractures * The time from diagnosis to surgery is more than 48 hours Exclusion Criteria: * Unable to walk about 3 meters or across a room without assistance before the fracture * Emergency surgery * Congestive heart failure, asthma, anemia (Hb \< 90 g/L), hypoalbuminemia (ALB \< 35g/L) * Abnormal coagulation function * Severe aortic stenosis * Injection site infection or increased intracranial pressure * Patients have participated in previous trials or have been determined by a surgeon or anesthesiologist to be unsuitable for randomization * The written informed consent of the patient or his/her representative cannot be obtained
Where it's running
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Tianzhu Liu
Wuhan, Hubei, China Recruiting
Study contacts
- Principal investigator: Tianzhu Liu, M.D. — Tongji Hospital
- Study coordinator: Tianzhu Liu, M.D.
- Email: liutzh@126.com
- Phone: 13098866448
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Patient-centered education after hip fracture surgery
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PENG Block Compared with Femoral Nerve Block for Spinal Anesthesia in Hip Fracture Surgery
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This will test whether giving one dose or two doses of tranexamic acid around surgery helps people aged 65 and older with pertrochanteric or subtrochanteric hip fractures lose less blood and need fewer transfusions.
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PENG block plus local infiltration analgesia for anterior-approach hip replacement
This test sees if a motor-sparing PENG block combined with local infiltration around the hip controls pain as well as spinal anesthesia for adults having anterior‑approach hip replacement.
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This will test whether a PENG nerve block or a femoral nerve block gives better pain relief and reduces opioid use for adults with confirmed hip fractures who agree to a nerve block.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.