Comparing scalp block and incisional infiltration for pain management after craniotomy

Comparison Of The Effect Of Scalp Block And Incision Sıte Infiltratıon Applied On Postoperative Acute Paın And Hemodynamics In Patients Undergoing Craniotomy

NA · Aydin Adnan Menderes University · NCT06264765

This study is testing whether a scalp block or an injection at the incision site works better for managing pain after brain surgery in adults.

Quick facts

PhaseNA
Study typeInterventional
Enrollment62 (estimated)
Ages18 Years to 75 Years
SexAll
SponsorAydin Adnan Menderes University (other)
Locations1 site (Aydın)
Trial IDNCT06264765 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to evaluate the effectiveness of scalp block versus incisional infiltration for managing postoperative pain in patients undergoing craniotomy. The study will involve routine anesthesia induction followed by either a scalp block or incisional infiltration before surgery begins. The primary focus is on assessing postoperative pain levels and hemodynamic stability, as both techniques have shown potential benefits in previous studies. The trial will include patients aged 18-75 with a Glasgow Coma Scale score greater than 13 who are undergoing elective craniotomy.

Who should consider this trial

Good fit: Ideal candidates for this study are patients aged 18-75 who are undergoing elective craniotomy and have a Glasgow Coma Scale score greater than 13.

Not a fit: Patients who may not benefit from this study include those with a Glasgow Coma Scale score less than 13, emergency surgery cases, or those with contraindications to local anesthetics.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management and reduced opioid consumption for patients after craniotomy.

How similar studies have performed: While there are limited studies directly comparing scalp block with incisional infiltration, existing research suggests both techniques can provide effective pain management and hemodynamic stability.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Patients who underwent craniotomy under elective conditions
2. ASA I-III
3. 18-75 years old
4. GCS \>13

Exclusion Criteria:

1. GCS \<13
2. Emergency surgery
3. Presence of contraindications to the LA agents used in this study
4. Chronic use of opioids
5. Psychiatric disorders
6. Presence of infection at the injection site
7. Uncontrolled intracranial hypertension
8. Chronic hypertension,
9. Coronary artery disease, arrhythmia,
10. Coagulopathy,
11. Patients who have previously undergone craniotomy

Where this trial is running

Aydın

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Hemodynamic Instability, scalp block, opioid consumption, postoperative pain

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.