Comparing robot-assisted training to standard training for stroke recovery
Official title: The Effect of Robot-Assisted Versus Standard Training on Motor Function Following Subacute Rehabilitation After Ischemic Stroke - a Randomised Controlled Trial Nested in a Prospective Cohort.
Run by Odense University Hospital · NCT06273475 · Data updated 2026-11-12
This study is testing if robot-assisted training can help people with moderate to severe stroke recover better than regular training.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 40 (estimated) |
| Sponsor | Odense University Hospital Academic / other |
| Locations | 2 sites (Copenhagen and 1 other locations) |
| Status | Recruiting |
| Started | May 1, 2024 |
| Main results expected | March 1, 2026 |
| Study ends | February 1, 2027 |
| Registry record updated | November 20, 2025 |
| Trial ID | NCT06273475 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are individuals aged 18 or older who are 6 to 24 months post-ischemic stroke and have moderate to severe impairments.
✕Probably not a fit
Patients with severe cognitive deficits, prior significant neurological conditions, or those unable to walk independently prior to their stroke may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized controlled trial aims to evaluate the effectiveness of robot-assisted training compared to standard training in improving motor function, physical function, fatigue, and quality of life in individuals with moderate to severe impairments following ischemic stroke. Participants will be recruited from multiple hospitals and will undergo training designed to alleviate the burden of body weight during rehabilitation. The study focuses on chronic stroke patients who have completed subacute rehabilitation and assesses various functional outcomes to determine the superiority of the robot-assisted approach.
Why it matters
Potential benefit: If successful, this study could lead to improved rehabilitation outcomes and quality of life for stroke survivors.
How similar studies have gone: Previous studies have shown promising results for robot-assisted rehabilitation in stroke recovery, indicating potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion: 1. Ischemic and haemorrhagic stroke 2. Chronic state (6-24 months post-stroke). 3. Subacute rehabilitation terminated (subacute phase defined as until 6 months post-stroke). 4. Moderately-severely impaired: 1. Modified Rankin Scale Score 3-5. 2. Scandinavian Stroke Scale Leg Motor Function Score 0-4 and/or SSS gait function 0-9. 5. Approved by referring doctor Exclusion: 1. Prior SAH 2. Infarct located in the cerebellum or brain stem 3. Severe fatigue making study completion improbable. 4. Cognitive deficits impeding study participation. 5. Inability to walk independently pre-stroke. 6. Recurrence of cardiovascular/cerebrovascular accidents. 7. Pre-existing neurological diseases or ongoing cancer treatment. 8. Refusing group allocation. 9. Concurrent participation in another clinical trial potentially interacting with the present trial.
Where it's running
-
Odense University Hospital
Odense, Denmark Recruiting -
Rigshospitalet and Herlev Gentofte Hospital
Copenhagen, Denmark Not yet recruiting
Study contacts
- Principal investigator: Jon Skovgaard Jensen, Ph.d.-student — Department of Clinical Research, University of Southern Denmark
- Study coordinator: Jon Skovgaard Jensen, Ph.d.-student
- Email: jskovgaard@health.sdu.dk
- Phone: +4530127595
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
AI-based tools to help diagnose, treat and predict stroke outcomes across multiple hospitals
This study tests AI-powered tools on real-world stroke patients to see if they can improve pre-hospital triage, diagnosis, and outcome prediction while data stay securely within each hospital.
-
Ear-based nerve stimulation to help sleep after a stroke
A device that delivers vagal nerve stimulation through the ear is tested to see if it helps stroke patients in rehab sleep better.
-
Remotely Delivered Step Count Rehab After Stroke
This study tests a remotely guided program that uses step counting and six clinician sessions to see if people who had a stroke can feasibly use it at home.
-
Virtual Stroke Unit care for patients in non-specialized hospitals
This study tests whether delivering stroke care remotely via a Virtual Stroke Unit is as safe and effective as traditional stroke units for adults with acute stroke who aren’t candidates for thrombectomy.
-
Best Care for Acute Stroke in General Wards
A nurse-led program called BEST CARE ICTUS_HC is tested in hospitals without Stroke Units to see if it reduces stroke complications and helps recovery after an acute ischemic or hemorrhagic stroke.
-
Savvy medication-support program for people after stroke
This project will test whether Savvy — short phone-based psychological exercises, a weekly pill organizer, and text reminders — helps stroke survivors take their blood-pressure medicines and improve blood pressure compared with usual care.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.