Comparing Remimazolam and Propofol for sedation during endoscopic procedures

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the efficacy and safety of Remimazolam, both alone and in combination with Propofol, for moderate sedation during endoscopic examinations and treatments. It is a prospective, randomized, single-center study where eligible patients will be divided into three groups: one receiving Propofol, another receiving Remimazolam, and the last receiving both medications. The study will monitor various parameters including anesthesia depth, vital signs, recovery times, and patient satisfaction to determine the best sedation approach.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Subjects are between 20-80 years old.
* Anesthesiologists rated ASA as between I and III.
* Patients undergoing upper gastrointestinal endoscopic examination or therapy.

Exclusion Criteria:

* Allergy to Propofol, Remimazolam, or opioid medications.
* Emergency surgery.
* Pregnancy.
* History of malignant hyperthermia.
* Impaired liver or kidney function.
* Airway difficulties due to pharyngeal tumors.
* Refusal to participate.

Where it's running

• Kaohsiung Veterans General Hospital
  Kaohsiung City, Taiwan Recruiting

Study contacts

• Principal investigator: Chia-Hao Yang, M.d — employe
• Study coordinator: Yuan-Yi Chia, M.D
• Email: yychia@vghks.gov.tw
• Phone: 886-7-342-2121

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Gut health follow-along with Peachbiotic in adults

  This single-arm study tests whether Peachbiotic taken daily for 12 weeks helps adults with gut symptoms feel better.

  Recruiting Peach Perfect · Las Vegas, Nevada · NCT07927907

• Prebiotic and Probiotic Combo for Constipation Symptoms

  This study tests whether adding 1-kestose to a probiotic (BBH112) helps adults with constipation-related symptoms see more relief and better quality of life.

  Recruiting Seoul National University Hospital · Seongnam-si, Gyeonggi-do · NCT07923279

• Prehabilitation with Resistance, Aerobic, or Both Before Colorectal Surgery

  Four pre-surgery exercise options (resistance, aerobic, both, or none) will be tested to see which best reduces complications after colorectal cancer surgery.

  Recruiting Semmelweis University · Budapest · NCT07896174

• Constipation Prevention Checklist in hip surgery patients

  A simple checklist is used to see if hip surgery patients can stay regular by staying hydrated, eating well, moving early, and using abdominal massage.

  Recruiting Cumhuriyet University · Sivas · NCT07895316

• Abdominal massage training for caregivers to help manage constipation

  Caregivers receive training to use abdominal massage and help their loved ones with constipation in palliative care to see if it improves symptoms and caregiver confidence.

  Recruiting Saglik Bilimleri Universitesi · Istanbul · NCT07886125

• HR20013 for preventing nausea and vomiting in cancer patients receiving chemotherapy

  This real-world study tests whether HR20013 helps prevent nausea and vomiting in adults with cancer who are getting chemotherapy.

  Recruiting Sun Yat-sen University · Guangzhou, Guangdong · NCT07874308

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.