Comparing recovery after knee surgery based on body composition
Association Between Phase Angle and Functional Recovery After Total Knee Arthroplasty
This study is trying to see if patients with knee osteoarthritis recover better after surgery based on their body composition, specifically looking at a measurement called phase angle.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 200 (estimated) |
| Ages | 55 Years and up |
| Sex | All |
| Sponsor | Yonsei University Academic / other |
| Locations | 1 site (Yongin-si, Gyeonggi-do) |
| Trial ID | NCT06701474 on ClinicalTrials.gov |
What this trial studies
This observational study aims to compare the functional recovery of patients with end-stage knee osteoarthritis before and after total knee arthroplasty, focusing on the phase angle level as a measure of body composition. Participants will undergo a series of assessments, including physical function tests, muscle strength evaluations, and bioelectrical impedance analysis, both preoperatively and three months post-surgery. The study seeks to determine if a low phase angle correlates with poorer recovery outcomes compared to a high phase angle. By analyzing these factors, researchers hope to gain insights into the relationship between body composition and postoperative recovery.
Who should consider this trial
Good fit: Ideal candidates are individuals aged 55 and over diagnosed with knee osteoarthritis who are planning to undergo total knee arthroplasty.
Not a fit: Patients with neurological disorders affecting gait, severe comorbidities, or recent knee surgeries may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could help identify patients at risk for poorer recovery after knee surgery, allowing for tailored preoperative interventions.
How similar studies have performed: While the specific focus on phase angle in relation to knee arthroplasty recovery is novel, similar studies have shown that body composition can impact surgical outcomes.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Individuals aged 55 and over (based on the age on their national ID at the time of consent) * Individuals diagnosed with knee OA based on medical history, physical examination, and radiographic assessments. * Individuals who plan to perform total knee arthroplasty Exclusion Criteria: * Individuals with gait disturbance due to neurologic disorders such as Parkinson disease, stroke and dementia * Individuals with severe cardiac, pulmonary, or musculoskeletal disorders that limited quadriceps strength and physical function * Individuals with knee osteoarthritis due to secondary causes such as rheumatic or traumatic arthritis * Individuals with a history of any knee surgery within one year. * Individuals considered clinically unsuitable for the study by the researchers or person in charge based on significant medical findings.
Where this trial is running
Yongin-si, Gyeonggi-do
- Yongin Severance Hospital — Yongin-si, Gyeonggi-do, South Korea (Recruiting)
Study contacts
- Study coordinator: Na Young Kim, MD, PhD
- Email: kny8452@yuhs.ac
- Phone: +82 010 9127 4482
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.