Comparing PTSD treatments for LGBTQIA+ individuals

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to evaluate the effectiveness of Cognitive Processing Therapy (CPT) and STAIR Narrative Therapy (SNT) in treating posttraumatic stress disorder (PTSD) among LGBTQIA+ adults. The study will assess the reduction of PTSD symptoms, improvement in quality of life, and changes in depression levels among participants. Additionally, it will explore how factors such as stigma, discrimination, and substance use may influence treatment outcomes. Participants will receive one of the two therapies and complete assessments before and after treatment to measure effectiveness.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. 18 years of age or older
2. Currently live in California
3. Ability to understand study procedures and to comply with them for the entire length of the study
4. Ability to understand a written informed consent document and the willing to sign it
5. Ability to speak and read English or Spanish
6. Identify as a sexual and/or gender minority
7. Score 33 or higher on the PTSD Checklist-5 (PCL-5)
8. Interest in getting treatment for PTSD
9. Not be in another concurrent psychotherapy treatment (group or individual) for PTSD (psychotherapy treatment for non-PTSD conditions is allowed).
10. Able to attend treatment sessions in person in San Francisco or have access to a device that allows for treatment via videoconferencing.

Exclusion Criteria:

1. Contraindication to any study-related procedure or assessment
2. Clinically significant impairment which interferes with ability to fully participate in the study (including symptoms of schizophrenia, schizoaffective disorder, bipolar disorder, or other disorders)
3. Active suicidal intent

Where it's running

• Stanford University
  Palo Alto, California, United States Recruiting
• UCSF Alliance Health Project
  San Francisco, California, United States Recruiting

Study contacts

• Principal investigator: Annesa P Flentje, PhD — Stanford University
• Study coordinator: Annesa P Flentje, PhD
• Email: lgbtqia_study@ucsf.edu
• Phone: 650-497-7112

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.