Comparing preoperative immunonutrition to standard nutrition for colorectal surgery patients

A Randomized Controlled Trial on Effect of Preoperative Immunonutrition Versus Standard Oral Nutrition in Patient Undergoing Colorectal Surgery.

Not applicable Interventional Hospital Universiti Sains Malaysia · NCT06128798

This study is testing if a special nutrition plan before colorectal surgery can help patients recover faster and have fewer complications compared to regular nutrition.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment58 (estimated)
Ages18 Years and up
SexAll
SponsorHospital Universiti Sains Malaysia Academic / other
Locations1 site (Kubang Kerian, Kelantan)
Trial IDNCT06128798 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to evaluate the effects of preoperative immunonutrition versus standard oral nutrition on patients undergoing colorectal cancer surgery. It is a randomized controlled trial that will assess whether immunonutrition can facilitate an earlier return of gastrointestinal function, reduce the risk of postoperative surgical site infections, and shorten hospital stays. The study will involve adult patients scheduled for laparoscopic elective colorectal surgery, with a focus on the nutritional support provided before the operation. The trial will utilize specific immunonutrition formulas that include arginine, omega-3 fatty acids, and nucleotides.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 and older who are scheduled for laparoscopic elective colorectal surgery.

Not a fit: Patients who are under 18 years old, have known allergies to milk, fish, or soy, or require emergency surgery may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to improved recovery times and reduced complications for patients undergoing colorectal surgery.

How similar studies have performed: Other studies have shown promising results with immunonutrition approaches in surgical settings, suggesting potential benefits in recovery and complication rates.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Age is at least 18 years old
2. All cases posted for Laparoscopic elective colorectal surgery

Exclusion Criteria:

1. Known allergy to milk, fish, and soy.
2. On fluid restriction
3. Emergency Surgery
4. Minor Age \< 18 years old

Where this trial is running

Kubang Kerian, Kelantan

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Colorectal NeoplasmsImmunonutritionColorectal CancerOral Impact
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.