Clinical trial Recruiting at 1 site Phase 4 Interventional Ages 18 to 70

Comparing pain relief methods for forearm surgery

Official title: Efficacy of Combined US-Guided Supraclavicular Block and Interscalene Analgesia Versus an Intercostobrachial Nerve Block Versus PCA With Fentanyl on Preventing Tourniquet Pain in Forearm Surgery: A Randomized Clinical Trial

Run by Al-Azhar University · NCT05602636 · Data updated 2026-11-12

This study is testing different pain relief methods for adults having forearm surgery to see which one works best during the procedure.

Quick facts

PhasePhase 4
Study typeInterventional
Ages18 Years to 70 Years
SexAll
Enrollment60 (estimated)
SponsorAl-Azhar University
Academic / other
Locations1 site (Damietta)
StatusRecruiting
StartedDecember 10, 2022
Main results expectedDecember 30, 2025
Study endsDecember 30, 2025
Registry record updatedJanuary 6, 2026
Trial IDNCT05602636 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults over 18 years old, classified as ASA I-III, and scheduled for surgery distal to the elbow requiring regional anesthesia.

Probably not a fit

Patients with contraindications to regional anesthesia or allergies to local anesthetics may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the effectiveness of different analgesic techniques for patients undergoing forearm surgery. It compares the Interscalene brachial plexus block (ISBPB), Intercostobrachial nerve block (ICBN), and Patient-Controlled Analgesia (PCA) with fentanyl against the Supraclavicular brachial plexus block (SCBPB) in managing tourniquet pain. The study will involve adult patients who are scheduled for orthopedic or plastic surgery with a tourniquet duration exceeding 45 minutes and who prefer regional anesthesia. The goal is to determine which method provides better pain relief during the procedure.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing forearm surgery.

How similar studies have gone: While there is limited research directly comparing these specific techniques, similar studies have shown varying degrees of success with regional anesthesia approaches.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* aged more than 18 years,
* ASAI-III patients
* scheduled to undergo orthopedic or plastic surgery distal to the elbow with an anticipated tourniquet duration greater than 45 min.
* desiring regional anesthesia as the primary anesthetic.

Exclusion Criteria:

* Contraindication to regional anesthesia.
* Allergy to local anesthetics.
* Primary block failure.
* If patients desired deep intraoperative sedation.
* Clinically significant cognitive impairment.

Where it's running

  • Facualty of Medicine(Damietta), Al Azhar University
    Damietta, Egypt
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.