Comparing pain relief methods for forearm surgery

Efficacy of Combined US-Guided Supraclavicular Block and Interscalene Analgesia Versus an Intercostobrachial Nerve Block Versus PCA With Fentanyl on Preventing Tourniquet Pain in Forearm Surgery: A Randomized Clinical Trial

Phase 4 Interventional Al-Azhar University · NCT05602636

This study is testing different pain relief methods for adults having forearm surgery to see which one works best during the procedure.

Quick facts

PhasePhase 4
Study typeInterventional
Enrollment60 (estimated)
Ages18 Years to 70 Years
SexAll
SponsorAl-Azhar University Academic / other
Locations1 site (Damietta)
Trial IDNCT05602636 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the effectiveness of different analgesic techniques for patients undergoing forearm surgery. It compares the Interscalene brachial plexus block (ISBPB), Intercostobrachial nerve block (ICBN), and Patient-Controlled Analgesia (PCA) with fentanyl against the Supraclavicular brachial plexus block (SCBPB) in managing tourniquet pain. The study will involve adult patients who are scheduled for orthopedic or plastic surgery with a tourniquet duration exceeding 45 minutes and who prefer regional anesthesia. The goal is to determine which method provides better pain relief during the procedure.

Who should consider this trial

Good fit: Ideal candidates are adults over 18 years old, classified as ASA I-III, and scheduled for surgery distal to the elbow requiring regional anesthesia.

Not a fit: Patients with contraindications to regional anesthesia or allergies to local anesthetics may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing forearm surgery.

How similar studies have performed: While there is limited research directly comparing these specific techniques, similar studies have shown varying degrees of success with regional anesthesia approaches.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* aged more than 18 years,
* ASAI-III patients
* scheduled to undergo orthopedic or plastic surgery distal to the elbow with an anticipated tourniquet duration greater than 45 min.
* desiring regional anesthesia as the primary anesthetic.

Exclusion Criteria:

* Contraindication to regional anesthesia.
* Allergy to local anesthetics.
* Primary block failure.
* If patients desired deep intraoperative sedation.
* Clinically significant cognitive impairment.

Where this trial is running

Damietta

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Forearm SurgeryUS-Guided Supraclavicular BlockInterscalene AnalgesiaTourniquet PainIntercostobrachial Nerve BlockPCA with Fentanyl
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.