Comparing pain relief methods during medical abortion

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates the effectiveness of non-steroidal anti-inflammatory drugs (NSAIDs) for pain management during medical abortion procedures for pregnancies between 13 and 22 weeks. Participants will be divided into two groups: one receiving NSAIDs prophylactically and the other receiving them on-demand as pain occurs. The study aims to determine if the prophylactic approach leads to better pain relief outcomes and to assess any potential adverse effects associated with NSAID use in this context. Pain levels will be monitored using validated scales throughout the procedure.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Pregnant women aged 18 years or older.
* No mental illness.
* Gestational age between 13 and 22 weeks (based on the last menstrual period with a regular menstrual cycle and accurate recall of the last menstrual period, or based on a first-trimester ultrasound) with an indication of stillbirth, fetal malformation requiring termination, or voluntary abortion with counseling and understanding of the abortion procedure.
* Willing to participate in the study.
* Capable of reading and signing the informed consent form.
* Able to provide personal information independently.

Exclusion Criteria:

* Medical conditions contraindicating medical abortion: bleeding disorders, anticoagulant use, moderate to severe anemia.
* Cardiovascular conditions: heart failure, mitral valve stenosis, embolism, uncontrolled hypertension.
* Other medical conditions: renal failure, adrenal gland disorders, severe asthma, liver and biliary diseases, glaucoma.
* Active pelvic inflammatory disease or acute genital infections.
* Previous uterine surgery.
* Placenta previa or central placenta previa.
* Uterine malformations.
* History of allergy to NSAIDs, Mifepristone, or Misoprostol.
* Unwillingness to participate in the study.

Where it's running

• Hung Vuong Hospital
  Ho Chi Minh City, Vietnam Recruiting

Study contacts

• Study coordinator: Le Trang, MD
• Email: lethikieutrang912@gmail.com
• Phone: +8434615919

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.