Comparing nerve stimulation and standard care for pain relief after knee surgery

Percutaneous Femoral Nerve Neuromodulation for Postoperative Analgesia and Functional Recovery Following Knee Arthroplasty.

Not applicable Interventional Hospital General Universitario de Valencia · NCT05971095

This study is testing if a new way of stimulating a nerve can help people feel less pain and recover better after knee surgery compared to regular care.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment64 (estimated)
Ages18 Years and up
SexAll
SponsorHospital General Universitario de Valencia Academic / other
Locations1 site (Valencia)
Trial IDNCT05971095 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to evaluate the effectiveness of percutaneous femoral nerve neuromodulation combined with a femoral nerve block in improving pain management and functional recovery in patients undergoing knee arthroplasty. Participants will undergo a procedure where electrodes are placed near the femoral nerve to assess the impact on quadriceps contraction force and analgesia compared to a control group receiving standard care. The study focuses on measuring the differences in postoperative pain relief and recovery outcomes between the two approaches.

Who should consider this trial

Good fit: Ideal candidates are adults over 18 years old who are undergoing knee arthroplasty and can provide informed consent.

Not a fit: Patients under 18, those with cognitive impairments, or contraindications for regional anesthesia may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to improved pain management and faster recovery for patients after knee surgery.

How similar studies have performed: While similar neuromodulation techniques have shown promise in pain management, this specific approach is relatively novel and has not been extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Over 18 years
* Those who sign the informed consent
* Not pregnant
* Cognitive capacity that allows subjective postoperative evaluations.

Exclusion Criteria:

* Under 18 years old
* IC rejection or withdrawal
* Pregnancy
* Cognitive impairment
* Contraindication for Regional Anesthesia

Where this trial is running

Valencia

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Acute PainPENSNeuromodulationPercutaneous peripheral nere stimulationPostoperative painAcute pain after surgeryTotal Knee arthtolasty
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.