Comparing MRI with other imaging techniques for breast cancer detection
Magnetic Resonance Imaging of Breast Cancer
This study tests if MRI is better at finding and describing breast cancer than other imaging methods in women who have already had a breast exam and mammogram.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 500 (estimated) |
| Ages | 21 Years and up |
| Sex | Female |
| Sponsor | Stanford University Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Stanford, California) |
| Trial ID | NCT01035112 on ClinicalTrials.gov |
What this trial studies
This study aims to evaluate the effectiveness of magnetic resonance imaging (MRI) in detecting and defining breast cancer compared to established diagnostic imaging methods. It involves female participants who have undergone a breast physical examination and mammography within the last three months, focusing on those with palpable or mammographically-detected suspicious breast lesions. The study will assess how well MRI can identify breast cancer and its characteristics, potentially leading to improved diagnostic accuracy.
Who should consider this trial
Good fit: Ideal candidates for this study are females with suspicious breast lesions detected through physical examination or mammography.
Not a fit: Patients who are male, pregnant, or have contraindications to MRI will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the early detection and characterization of breast cancer, leading to better treatment outcomes for patients.
How similar studies have performed: Other studies have shown promising results in using MRI for breast cancer detection, indicating that this approach is supported by prior research.
Eligibility criteria
Show full inclusion / exclusion criteria
INCLUSION CRITERIA * Female * Documented breast physical examination, * Documented mammography within 3 months of the MR studies * Palpable or mammographically-detected suspect breast lesions * Women who have already undergone lumpectomy for breast cancer and have post-biopsy/post-radiation changes will be eligible if they have mammographically-detected or palpable breast abnormalities which are sufficiently suspicious to merit core needle or surgical biopsy. EXCLUSION CRITERIA: * Male by birth * Able to complete the MR examination. Subjects will be interviewed by one of the investigators for the usual contraindications to * MR contraindications including * Pacemakers * Metallic implants * Severe claustrophobia * Aneurysm clips * Pregnancy * Current lactation * Other conditions precluding proximity to a strong magnetic field. * Received an enhanced MR procedure within 48 hours, * Iodinated contrast within six hours, * Known sensitivity to MR contrast agents, * Not likely to complete the study in full or * Other clinical reason which would preclude participation in the protocol.
Where this trial is running
Stanford, California
- Stanford University School of Medicine — Stanford, California, United States (Recruiting)
Study contacts
- Principal investigator: Bruce L Daniel — Stanford University
- Study coordinator: Jocelyn Steffan
- Email: jsteffen@stanford.edu
- Phone: 650-725-1812
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.