Clinical trial Recruiting at 1 site Interventional Ages 17 to 75

Comparing morning and evening aerobic exercise for heart recovery after a heart attack

Official title: The Effect of Morning vs Evening Aerobic Exercise Training on Cardiac Remodeling and Function Improvement in Patients After ST Elevation Myocardial Infarction

Run by RenJi Hospital · NCT06385834 · Data updated 2026-11-12

This study tests whether doing aerobic exercise in the morning or evening helps heart recovery better for people who have had a heart attack.

More ST-segment Elevation Myocardial Infarction (STEMI) trials

Quick facts

Study typeInterventional
Ages17 Years to 75 Years
SexAll
Enrollment201 (estimated)
SponsorRenJi Hospital
Academic / other
Locations1 site (Shanghai)
StatusRecruiting
StartedApril 30, 2024
Main results expectedApril 30, 2028
Study endsJuly 30, 2028
Registry record updatedDecember 31, 2024
Trial IDNCT06385834 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 to 75 who have recently experienced a STEMI and have undergone complete revascularization.

Probably not a fit

Patients with unstable angina, severe heart failure, or other serious health conditions may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of aerobic exercise timing on cardiac remodeling and function in patients who have experienced an ST-segment Elevation Myocardial Infarction (STEMI). Participants will engage in either morning or evening aerobic exercise to determine which timing yields optimal cardiovascular benefits. The research aims to understand how the circadian rhythm influences the effectiveness of exercise in improving heart health post-STEMI. By analyzing the outcomes, the study seeks to provide evidence-based recommendations for exercise timing in cardiac rehabilitation.

Why it matters

Potential benefit: If successful, this study could lead to improved recovery and reduced mortality rates for patients after a heart attack.

How similar studies have gone: While there is evidence supporting the benefits of aerobic exercise post-STEMI, the specific focus on exercise timing is a novel approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Between 18 and 75-years-old;
* Typical symptoms of acute myocardial infarction within 24 hours, with ST segment elevation of ≥1mm in two consecutive leads on electrocardiogram
* After receiving complete revascularization treatment
* Cardiac function grading I to II without any other serious complications
* Left ventricular ejection fraction \>30%
* Compliant with the guidelines of the American College of Cardiology/American Heart Association for participating in cardiac rehabilitation standards
* Signed written informed consent.

Exclusion Criteria:

* Patients with unstable angina
* severe symptomatic congestive heart failure detectable myocardial ischemia
* valvular disease requiring surgery
* severe ventricular arrhythmias
* severe concomitant life-threatening diseases such as cancer, and rheumatoid disease
* osteoarticular diseases that may affect the exercise process

Where it's running

  • Renji Hospital
    Shanghai, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.