Comparing morning and evening aerobic exercise for heart recovery after a heart attack
The Effect of Morning vs Evening Aerobic Exercise Training on Cardiac Remodeling and Function Improvement in Patients After ST Elevation Myocardial Infarction
This study tests whether doing aerobic exercise in the morning or evening helps heart recovery better for people who have had a heart attack.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 201 (estimated) |
| Ages | 17 Years to 75 Years |
| Sex | All |
| Sponsor | RenJi Hospital Academic / other |
| Locations | 1 site (Shanghai) |
| Trial ID | NCT06385834 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of aerobic exercise timing on cardiac remodeling and function in patients who have experienced an ST-segment Elevation Myocardial Infarction (STEMI). Participants will engage in either morning or evening aerobic exercise to determine which timing yields optimal cardiovascular benefits. The research aims to understand how the circadian rhythm influences the effectiveness of exercise in improving heart health post-STEMI. By analyzing the outcomes, the study seeks to provide evidence-based recommendations for exercise timing in cardiac rehabilitation.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 to 75 who have recently experienced a STEMI and have undergone complete revascularization.
Not a fit: Patients with unstable angina, severe heart failure, or other serious health conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved recovery and reduced mortality rates for patients after a heart attack.
How similar studies have performed: While there is evidence supporting the benefits of aerobic exercise post-STEMI, the specific focus on exercise timing is a novel approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Between 18 and 75-years-old; * Typical symptoms of acute myocardial infarction within 24 hours, with ST segment elevation of ≥1mm in two consecutive leads on electrocardiogram * After receiving complete revascularization treatment * Cardiac function grading I to II without any other serious complications * Left ventricular ejection fraction \>30% * Compliant with the guidelines of the American College of Cardiology/American Heart Association for participating in cardiac rehabilitation standards * Signed written informed consent. Exclusion Criteria: * Patients with unstable angina * severe symptomatic congestive heart failure detectable myocardial ischemia * valvular disease requiring surgery * severe ventricular arrhythmias * severe concomitant life-threatening diseases such as cancer, and rheumatoid disease * osteoarticular diseases that may affect the exercise process
Where this trial is running
Shanghai
- Renji Hospital — Shanghai, China (Recruiting)
Study contacts
- Study coordinator: Jun PU, MD
- Email: pujun310@hotmail.com
- Phone: 13817577592
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.