Comparing morning and evening aerobic exercise for heart recovery after a heart attack
Official title: The Effect of Morning vs Evening Aerobic Exercise Training on Cardiac Remodeling and Function Improvement in Patients After ST Elevation Myocardial Infarction
Run by RenJi Hospital · NCT06385834 · Data updated 2026-11-12
This study tests whether doing aerobic exercise in the morning or evening helps heart recovery better for people who have had a heart attack.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 17 Years to 75 Years |
| Sex | All |
| Enrollment | 201 (estimated) |
| Sponsor | RenJi Hospital Academic / other |
| Locations | 1 site (Shanghai) |
| Status | Recruiting |
| Started | April 30, 2024 |
| Main results expected | April 30, 2028 |
| Study ends | July 30, 2028 |
| Registry record updated | December 31, 2024 |
| Trial ID | NCT06385834 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 to 75 who have recently experienced a STEMI and have undergone complete revascularization.
✕Probably not a fit
Patients with unstable angina, severe heart failure, or other serious health conditions may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the effects of aerobic exercise timing on cardiac remodeling and function in patients who have experienced an ST-segment Elevation Myocardial Infarction (STEMI). Participants will engage in either morning or evening aerobic exercise to determine which timing yields optimal cardiovascular benefits. The research aims to understand how the circadian rhythm influences the effectiveness of exercise in improving heart health post-STEMI. By analyzing the outcomes, the study seeks to provide evidence-based recommendations for exercise timing in cardiac rehabilitation.
Why it matters
Potential benefit: If successful, this study could lead to improved recovery and reduced mortality rates for patients after a heart attack.
How similar studies have gone: While there is evidence supporting the benefits of aerobic exercise post-STEMI, the specific focus on exercise timing is a novel approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Between 18 and 75-years-old; * Typical symptoms of acute myocardial infarction within 24 hours, with ST segment elevation of ≥1mm in two consecutive leads on electrocardiogram * After receiving complete revascularization treatment * Cardiac function grading I to II without any other serious complications * Left ventricular ejection fraction \>30% * Compliant with the guidelines of the American College of Cardiology/American Heart Association for participating in cardiac rehabilitation standards * Signed written informed consent. Exclusion Criteria: * Patients with unstable angina * severe symptomatic congestive heart failure detectable myocardial ischemia * valvular disease requiring surgery * severe ventricular arrhythmias * severe concomitant life-threatening diseases such as cancer, and rheumatoid disease * osteoarticular diseases that may affect the exercise process
Where it's running
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Renji Hospital
Shanghai, China Recruiting
Study contacts
- Study coordinator: Jun PU, MD
- Email: pujun310@hotmail.com
- Phone: 13817577592
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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This study is testing a new tool that uses advanced computer technology to help doctors quickly and accurately diagnose serious heart problems in patients who come to the emergency room with chest pain or trouble breathing.
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.