Comparing magnesium sulfate doses in obese patients during surgery
Best Dose of Magnesium Sulfate Infusion in Obese. A Blind and Randomized Trial
This study is testing whether giving different amounts of magnesium sulfate based on actual or ideal body weight can help manage pain better for obese patients during surgery.
Quick facts
| Phase | Phase 3 |
|---|---|
| Study type | Interventional |
| Enrollment | 75 (estimated) |
| Ages | 18 Years to 60 Years |
| Sex | All |
| Sponsor | University of Sao Paulo General Hospital Academic / other |
| Locations | 2 sites (São José Dos Campos, SP and 1 other locations) |
| Trial ID | NCT04645719 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the optimal dosing of magnesium sulfate for analgesia in obese patients undergoing laparoscopic, bariatric, or cholecystectomy surgery. It aims to compare the effects of magnesium sulfate administered based on actual body weight versus corrected ideal body weight. A total of 75 participants will be randomly assigned to one of three groups: a control group receiving only general anesthesia, a group receiving magnesium sulfate based on real weight, and a group receiving it based on corrected ideal weight. The study seeks to determine which dosing strategy provides better pain management and outcomes for obese patients.
Who should consider this trial
Good fit: Ideal candidates are obese patients aged 18 to 60 scheduled for laparoscopic, bariatric, or cholecystectomy surgery.
Not a fit: Patients with heart block, neuropsychiatric impairments, or those using illicit drugs may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management protocols for obese patients undergoing surgery.
How similar studies have performed: While magnesium sulfate has been used in various clinical settings, this specific dosing comparison in obese patients is novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: healthy patients, patients with controlled systemic disease (arterial hypertension, endocrine disease), obese patients. - Exclusion Criteria: heart block, illicit drugs use, with neuropsychiatric impairment, in blockers calcium channels and with renal impairment
Where this trial is running
São José Dos Campos, SP and 1 other locations
- Sebastião Ernesto Silva Filho — São José Dos Campos, Sp, Brazil (Not_yet_recruiting)
- Hospital das Clínicas - Faculdade de Medicina da Universidade de Sao Paulo — São Paulo, Brazil (Recruiting)
Study contacts
- Principal investigator: sebastião silva filho — Hospital da Sociedade de Beneficência Portuguesa d
- Study coordinator: sebastião silva filho
- Email: sebasernesto@gmail.com
- Phone: 12991457764
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.