Comparing intensive and standard treatment for PTSD in adults

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to compare a novel intensive treatment format of prolonged exposure therapy with the standard weekly prolonged exposure therapy for adults suffering from post-traumatic stress disorder (PTSD). Participants will be randomly assigned to either receive the intensive treatment over 5 days with follow-up booster sessions or the traditional weekly sessions over 15 weeks. The study will evaluate the efficacy, mechanisms of change, and cost-effectiveness of the intensive approach in regular psychiatric care in Sweden. The goal is to determine if the intensive format can improve retention rates and recovery times for patients with PTSD.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 18 years of age or above,
* Primary PTSD diagnosis
* Fluent in Swedish
* Sign informed consent
* Able to attend either I-PE or 15 weekly sessions of PE

Exclusion Criteria:

* Initiation or adjustment of any psychotropic medication within the last 4 weeks prior to commencement of treatment
* Serious mental health symptoms, such as mania, psychosis, alcohol, or substance use disorders or current suicide risk warranting immediate clinical attention
* Ongoing evidence-based trauma-focused psychological treatment
* Ongoing trauma-related threat (e.g. living with a violent spouse)

Where it's running

• Traumaprogrammet, Psykiatri Sydväst
  Stockholm, Sweden Recruiting

Study contacts

• Study coordinator: Maria Bragesjö, PhD
• Email: maria.bragesjo@ki.se
• Phone: 0703399387

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.