Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Comparing inspiratory muscle training and Baduanjin exercises for heart health

Official title: Comparison of the Effects of Inspiratory Muscle Training and Baduanjin Exercises on Pulmonary Function, Exercise Capacity and Quality of Life in Patients With Hypertrophic Cardiomyopathy

Run by Istanbul University - Cerrahpasa · NCT06490250 · Data updated 2026-11-12

This study tests whether breathing exercises or a special exercise program can help people with hypertrophic cardiomyopathy improve their lung function, exercise ability, and overall quality of life.

More Hypertrophic Cardiomyopathy trials

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment51 (estimated)
SponsorIstanbul University - Cerrahpasa
Academic / other
Locations1 site (Istanbul)
StatusRecruiting
StartedOctober 25, 2024
Main results expectedJuly 30, 2025
Study endsNovember 30, 2025
Registry record updatedJune 15, 2025
Trial IDNCT06490250 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults over 18 with a left ventricular wall thickness of 15 mm or more and stable symptoms of hypertrophic cardiomyopathy.

Probably not a fit

Patients with acute heart failure, significant coronary artery disease, or severe comorbidities may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study compares the effects of inspiratory muscle training and Baduanjin exercises on pulmonary function, exercise capacity, and quality of life in patients with hypertrophic cardiomyopathy. It involves three groups: a control group, an inspiratory muscle training group using a specialized device, and a Baduanjin exercise group participating in a structured exercise program. Each intervention lasts for 8 weeks, with the aim of identifying effective methods to improve health outcomes for these patients.

Why it matters

Potential benefit: If successful, this study could enhance pulmonary function and quality of life for patients with hypertrophic cardiomyopathy.

How similar studies have gone: Previous studies have shown benefits of inspiratory muscle training, but the combination with Baduanjin exercises in this context is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Myocardial thickness in any region of the left ventricle is 15 mm or more on echocardiography or cardiac MRI
* Clinically and hemodynamically stable (patients with NYHA Class I and II)
* Patients over 18 years of age
* Patients who provide informed consent

Exclusion Criteria:

* Acute decompensated heart failure
* Decreased ejection fraction (\<40%)
* Unstable angina pectoris
* Significant coronary artery disease (CAD)
* Severe renal dysfunction (estimated glomerular filtration rate \<30 mL/min/m²)
* Uncontrolled hypertension (despite medication)
* Severe valve disease (moderate-severe aortic stenosis, advanced mitral regurgitation)
* Severe neurological disorders causing autonomic dysfunction
* Cognitive impairment that prevents communication
* Recent fractures, osteoporosis, presence of tumors, pregnancy, or back and spine problems

Where it's running

  • Istanbul University-Cerrahpasa (IUC) Cardiology Institute
    Istanbul, Turkey (Türkiye)
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.