Comparing fixed-rate versus time-programmed decreasing IV PCA after surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults having elective mixed surgery will receive intravenous patient-controlled analgesia programmed either as a fixed-rate basal infusion or as a time-programmed decremental background infusion. The study will compare total opioid consumption, postoperative pain scores, and the incidence of opioid-related adverse events between the two infusion modes. Patients aged 18–65 with ASA physical status I–III who meet eligibility criteria will be enrolled at Beijing Tiantan Hospital and assigned to one of the two PCA strategies. Results are intended to support more individualized and time-adaptive postoperative pain management.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* aged between 18 to 65 years;
* American Society of Anesthesiologists physical status Ⅰ - Ⅲ;
* Patients scheduled for elective mixed surgery were enrolled. Mixed surgeries included thoracoscopic surgery, laparoscopic surgery, hysteroscopy surgery, laparotomy, thoracotomy, open spinal surgery, craniotomy, and so on.

Exclusion Criteria:

* Chronic pain syndromes;
* Psychiatric disorders;
* Severe cardiovascular or cerebrovascular disease, renal or hepatic functional dysfunction, or allergic to PCA medications.

Where it's running

• Beijing Tiantan Hospital, Beijing, Beijing 100070
  Beijing, China Recruiting

Study contacts

• Study coordinator: Fang Luo
• Email: 13611326978@163.com
• Phone: 59976661

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.