Comparing adjustable feedback IV patient-controlled pain pumps with fixed-rate pumps after surgery.

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This trial enrolls adults aged 18–65 undergoing elective mixed surgeries and compares two intravenous patient-controlled analgesia (PCA) modes: a traditional fixed-rate basal infusion and a variable-rate feedback infusion. Participants will be assigned to receive one of the two PCA modes postoperatively and their cumulative opioid consumption, pain scores, and opioid-related adverse events will be recorded. The hypothesis is that the variable-rate feedback mode can better match changing postoperative pain, reduce total opioid use, and lower side effects compared with fixed-rate delivery. Results aim to provide evidence to support more individualized and intelligent postoperative analgesia protocols.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* aged between 18 to 65 years;
* American Society of Anesthesiologists physical status Ⅰ - Ⅲ;
* Patients scheduled for elective mixed surgery were enrolled. Mixed surgeries included thoracic, abdominal, spinal, orthopaedic, and cranial procedures performed using either minimally invasive or open approaches.

Exclusion Criteria:

* Allergy to PCA medications;
* Presence of chronic pain syndromes;
* Presence of psychiatric disorders, or severe cardiovascular, cerebrovascular, renal, or hepatic dysfunction.

Where it's running

• Beijing Tiantan Hospital, Beijing, Beijing 100070
  Beijing, China Recruiting

Study contacts

• Study coordinator: Fang Luo
• Email: 13611326978@163.com
• Phone: 13611326978

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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  Recruiting Phase 3 Hospital for Special Surgery, New York · New York, New York · NCT07864896

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.