Comparing EMDR therapy and SSRIs for treating PTSD
Official title: Efficacy of Eye Movement Desensitization and Reprocessing (EMDR) Therapy Versus Selective Serotonin Reuptake Inhibitors (SSRIs) in the Treatment of Post-Traumatic Stress Disorder: A Randomized Controlled Trial
Run by Combined Military Hospital Nowshera · NCT06955845 · Data updated 2026-05-14
This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.
This study is testing whether EMDR therapy can help adults with PTSD feel better compared to taking SSRIs over six weeks.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 60 Years |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Combined Military Hospital Nowshera Government |
| Locations | 2 sites (Nowshera, KPK and 1 other locations) |
| Trial ID | NCT06955845 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18-60 with a clinical diagnosis of PTSD lasting at least six months.
✕Probably not a fit
Patients with current substance abuse, psychotic disorders, bipolar disorder, or active suicidal ideation may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized controlled trial compares the effectiveness of Eye Movement Desensitization and Reprocessing (EMDR) therapy with Selective Serotonin Reuptake Inhibitors (SSRIs) in treating adults diagnosed with Post-Traumatic Stress Disorder (PTSD). Participants aged 18-60 will be randomly assigned to receive either EMDR therapy or SSRIs for six weeks. The primary outcome will be the rate of remission measured by validated PTSD symptom severity scales at Week 6, while secondary outcomes will assess changes in functional impairment and quality of life. The study aims to evaluate whether EMDR can serve as a non-pharmacological alternative to SSRIs for PTSD symptom relief.
Why it matters
Potential benefit: If successful, this study could provide an effective non-drug treatment option for patients suffering from PTSD.
How similar studies have gone: Other studies have shown promising results for EMDR therapy in treating PTSD, indicating that this approach is supported by existing evidence.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Age 18-60 years Clinical diagnosis of Post-Traumatic Stress Disorder (PTSD) Duration of illness ≥ 6 months Able to provide informed consent Exclusion Criteria: Current substance abuse or dependence History of psychotic disorder or bipolar disorder Active suicidal ideation Concurrent psychotherapy or psychiatric medication (except study-assigned SSRI)
Where it's running
-
Department of Psychiatry, Combined Military Hospital Nowshera
Nowshera, Kpk, Pakistan Recruiting -
Combined Military Hospital
Nowshera, Kpk, Pakistan Not yet recruiting
Study contacts
- Principal investigator: Asad Ullah Jan, MBBS,FCPS — CMH Nowshera
- Study coordinator: Asad Ullah Jan, MBBS, FCPS( Psychiatry)
- Email: asad2097@gmail.com
- Phone: +923445515919
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.