Comparing electrical muscle stimulation and resistive training for hemodialysis patients

Electrical Muscle Stimulation Versus Resistive Training On Physical Measures, And Fatigue In Hemodialysis Patients

Not applicable Interventional Cairo University · NCT06079502

This study is testing whether electrical muscle stimulation or resistance training helps people on hemodialysis feel stronger and less tired.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment60 (estimated)
Ages40 Years to 55 Years
SexAll
SponsorCairo University Academic / other
Locations1 site (Dokki)
Trial IDNCT06079502 on ClinicalTrials.gov

What this trial studies

This study aims to compare the effects of intradialytic neuromuscular electrical stimulation (NMES) and a resistive training program on physical performance, dialysis efficiency, and fatigue levels in patients undergoing hemodialysis. It will involve patients aged 40 to 55 years with chronic kidney failure on hemodialysis for over three years. The study is unique as it is the first to directly compare these two interventions in this patient population, building on previous research that examined each method separately.

Who should consider this trial

Good fit: Ideal candidates are patients aged 40 to 55 years with chronic kidney failure on hemodialysis for more than three years and a BMI between 25 and 29.9 kg/m2.

Not a fit: Patients with cognitive impairments, uncontrolled hypertension, or other serious health conditions such as coronary artery disease or diabetes may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved physical performance and reduced fatigue in hemodialysis patients.

How similar studies have performed: While previous studies have shown the effects of NMES and resistive training individually, this study's comparative approach is novel and has not been extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients of both sexes, with CKF on HD for more than 3 years.
* Age between 40 to 55 years old.
* BMI is between 25 and 29.9 kg/m2.

Exclusion Criteria:

Patients who have one of the following contraindications to the interventions or affect the results

* Cognitive impairment that prevented them from performing the evaluations and who were unable to understand and sign the written informed consent.
* Stroke
* Smokers
* Anemic patients
* Osteoarticular or disabling musculoskeletal disorders
* Uncontrolled hypertension (systolic blood pressure\>230 mm Hg and diastolic blood pressure\>120 mm Hg)
* Patients with coronary artery disease or heart failure.
* Diabetic patients
* Infectious diseases and chest diseases
* Active smokers' patients with peripheral vascular disease in the lower limbs such as deep vein thrombosis or thromboangiitis

Where this trial is running

Dokki

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions HemodialysisFatigue
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.