Comparing different ways to give dexmedetomidine to reduce postoperative delirium in older patients
Effect of Different Administration Routes of Dexmedetomidine on Postoperative Delirium in Elderly Patients Undergoing General Anesthesia
This study tests different ways to give a medication called dexmedetomidine to see if it can help older patients avoid confusion after surgery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 120 (estimated) |
| Ages | 65 Years to 99 Years |
| Sex | All |
| Sponsor | Boston Intelligent Medical Research Center, Shenzhen United Scheme Technology Co., Ltd. Industry-sponsored |
| Locations | 1 site (Zhongshan, Guangdong) |
| Trial ID | NCT05952050 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of various administration routes of dexmedetomidine, including intravenous, intratracheal, and intranasal, on the incidence of postoperative delirium in elderly patients undergoing general anesthesia. By comparing these methods, the research aims to identify the most effective and convenient route for minimizing delirium after surgery. The study focuses on patients aged 65 and older who are expected to be under general anesthesia for more than two hours. The findings could provide valuable insights into improving postoperative care for this vulnerable population.
Who should consider this trial
Good fit: Ideal candidates for this study are elderly patients over 65 years old who will undergo general anesthesia for more than two hours.
Not a fit: Patients who are younger than 65 years or those not undergoing general anesthesia may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved management of postoperative delirium, enhancing recovery and quality of life for elderly patients.
How similar studies have performed: Previous studies have shown that intravenous dexmedetomidine can reduce postoperative delirium, and this study explores additional routes, making it a novel approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Older than 65 years; General anesthesia for more than two hours; Exclusion Criteria: -
Where this trial is running
Zhongshan, Guangdong
- Weitao Chen — Zhongshan, Guangdong, China (Recruiting)
Study contacts
- Study coordinator: Weitao Chen
- Email: 540138690@qq.com
- Phone: 18025661798
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.