Comparing different volumes of local anesthetic for pain relief after thoracotomy

Comparison of Different Local Anesthetic Volumes of Thoracic Paravertebral Block Application in Post-thoracotomy Analgesia

Not applicable Interventional Ankara City Hospital Bilkent · NCT05700357

This study is testing which amount of local anesthetic works best to relieve pain after surgery for people having a thoracotomy.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment75 (estimated)
Ages18 Years to 80 Years
SexAll
SponsorAnkara City Hospital Bilkent Academic / other
Locations1 site (Çankaya, Ankara)
Trial IDNCT05700357 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the effectiveness of three different volumes (20 ml, 25 ml, and 30 ml) of thoracic paravertebral block (TPVB) using 0.25% bupivacaine for postoperative analgesia in patients undergoing elective thoracotomy. Thoracotomy is known to cause severe acute pain, and effective pain management is crucial to reduce postoperative complications and chronic pain development. By comparing these volumes, the study seeks to determine the optimal dose for pain relief while minimizing side effects. The findings could help establish a standardized approach to analgesia in thoracotomy patients.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 to 80 years, classified as ASA physical status I-III, with a BMI between 18 and 40, who are scheduled for elective thoracotomy.

Not a fit: Patients who may not benefit from this study include those undergoing emergency thoracotomy or those with a history of chronic opioid or analgesic use.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management protocols for patients undergoing thoracotomy, enhancing recovery and reducing complications.

How similar studies have performed: Previous studies have shown varying success with TPVB for postoperative analgesia, but this specific comparison of local anesthetic volumes is less commonly explored.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 18 to 80 years old
* American Society of Anesthesiologists (ASA) physical status I-II-III
* BMI 18 to 40 kg/m2
* Elective thoracotomy surgery

Exclusion Criteria:

* Patient refusing the procedure
* Emergency surgery
* History of chronic opioid or analgesic used

Where this trial is running

Çankaya, Ankara

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Thoracic Paravertebral BlockThoracotomyPostoperative AnalgesiaAcute PainLocal Anesthetic
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.