Comparing different pulse oximeters with arterial blood gas measurements
OxyGap : Comparison Between Different Pulse Oximeter and With the Arterial Blood
This study is testing how accurately different pulse oximeters measure oxygen levels in intensive care patients receiving oxygen therapy compared to standard blood tests.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 300 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Laval University Academic / other |
| Locations | 2 sites (Montreal, Quebec and 1 other locations) |
| Trial ID | NCT04772183 on ClinicalTrials.gov |
What this trial studies
This observational study evaluates the accuracy of various pulse oximeters (Nonin, Masimo, Philips, Nellcor) in measuring oxygen saturation in intensive care patients undergoing oxygen therapy. By comparing the pulse oximeter readings (SpO2) with the reference arterial blood gas measurements (SaO2), the study aims to identify the precision and biases of these devices. The findings will help refine recommendations for optimal oxygenation practices, addressing the variability in oximeter performance that can impact patient care.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older who are admitted to the Intensive Care Unit and have an arterial catheter already installed.
Not a fit: Patients who may not benefit from this study include those with no signal detected by the oximeter, pigmented nails or nail polish, methemoglobinemia, or those in isolation due to multi-resistant bacteria or COVID-19.
Why it matters
Potential benefit: If successful, this study could lead to improved oxygen therapy practices, enhancing patient safety and outcomes in intensive care settings.
How similar studies have performed: While the approach of comparing different pulse oximeters is common, this specific study's focus on precision and systematic biases in clinical practice is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * ≥ 18 years old * Patients admitted to the Intensive Care Unit * Artery catheter already installed Exclusion Criteria: * No signal with the oximeter * Pigmented nails or nail polish * Methemoglobinemia * Patient in isolation (multi-resistant bacteria, C-Difficile, COVID-19…) * Prone position
Where this trial is running
Montreal, Quebec and 1 other locations
- Chum — Montreal, Quebec, Canada (Not_yet_recruiting)
- Institut Universitaire de Cardiologie et de Pneumologie de Québec — Québec, Canada (Recruiting)
Study contacts
- Study coordinator: François Lellouche
- Email: francois.lellouche@criucpq.ulaval.ca
- Phone: 418-656-8711
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.