Comparing different methods of liver biopsy for diagnosing liver diseases
Prospective Single Centre Observational Study to Compare the Diagnostic Yield of Different Modalities of Liver Biopsy
This study is testing whether a new way of taking liver biopsies using endoscopic ultrasound is better than traditional methods for diagnosing liver diseases in adults.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 200 (estimated) |
| Ages | 18 Years to 100 Years |
| Sex | All |
| Sponsor | Nottingham University Hospitals NHS Trust Academic / other |
| Locations | 1 site (Nottingham) |
| Trial ID | NCT05912179 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate the diagnostic yield of endoscopic ultrasound (EUS) guided liver biopsy compared to traditional liver biopsy techniques such as percutaneous and transjugular methods. By collecting data from adult patients undergoing these procedures at a single tertiary hospital over a year, the study will assess the accuracy, complication rates, and overall effectiveness of each biopsy method. The findings could provide insights into the advantages of EUS in terms of diagnostic adequacy and patient outcomes.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 years or older who are scheduled to undergo any form of liver biopsy.
Not a fit: Patients under 18 years of age will not benefit from this study as they are excluded from participation.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnostic techniques for liver diseases, potentially reducing waiting times and enhancing patient care.
How similar studies have performed: While traditional liver biopsy methods are well-established, the use of EUS for liver biopsy is emerging and may not have extensive prior studies demonstrating its success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18 years or older * underwent liver biopsy either through EUS, percutaneous or transjugular route Exclusion Criteria: - under 18 years of age
Where this trial is running
Nottingham
- Nottingham University Hospitals NHS Trust — Nottingham, United Kingdom (Recruiting)
Study contacts
- Principal investigator: Suresh Vasan Suresh Vasan — Nottingham University Hospitals
- Study coordinator: Suresh Vasan Venkatachalapathy
- Email: suresh.venkatachalapathy@nuh.nhs.uk
- Phone: 07966968417
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.