Comparing different doses of truncal blocks for arm surgeries
Comparison of the Anesthetic and Analgesic Efficacy of Selective Truncal Blocks at Different Volumes in Upper Extremity Orthopedic Surgeries
This study is testing different amounts of local anesthesia for arm surgeries to see which dose works best for pain relief and how quickly it takes effect.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | Gaziosmanpasa Research and Education Hospital Government |
| Locations | 1 site (Istanbul) |
| Trial ID | NCT06664203 on ClinicalTrials.gov |
What this trial studies
This study aims to evaluate the effectiveness of selective truncal blocks using varying doses and volumes of local anesthetic for anesthesia in patients undergoing surgeries of the hand, wrist, forearm, and elbow. The primary focus is on the onset times of motor and sensory blocks, with successful anesthesia defined as the completion of surgery under regional anesthesia. Secondary outcomes will assess motor block duration, analgesia duration, and potential complications associated with the procedure.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18-65 with ASA scores of 1-2 undergoing upper extremity orthopedic surgeries, excluding shoulder procedures.
Not a fit: Patients with severe pulmonary disease, uncontrolled diabetes, or those with allergies to local anesthetics may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could enhance pain management and reduce complications during upper limb surgeries.
How similar studies have performed: Previous studies have shown promising results with peripheral nerve blocks in upper extremity surgeries, indicating that this approach is supported by existing evidence.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * ASA 1-2 * Body Mass Index (BMI) of 18-35 kg/m² * Age: 18-65 years -Patients undergoing all upper extremity orthopedic surgeries, except shoulder surgeries (distal humerus, elbow, forearm, hand, and wrist), will be included. - Exclusion Criteria: * Patient refusal * Pregnancy or breastfeeding * Severe pulmonary disease * Contralateral diaphragm paralysis * Nerve injury secondary to trauma * Neuromuscular disease * Peripheral neuropathy * Bleeding diathesis * Allergy to local anesthetics and dexamethasone * Uncontrolled diabetes mellitus * Morbid obesity with BMI \>35 * Severe cardiovascular, renal, or hepatic disease * Infection at the site of the nerve block
Where this trial is running
Istanbul
- Gaziosmanpasa Research and Training Hospital — Istanbul, Turkey (Türkiye) (Recruiting)
Study contacts
- Principal investigator: Serpil Sehirlioglu, MD — Gaziosmanpasa Research and Training Hospital
- Study coordinator: serpil Sehirlioglu, MD
- Email: drserpilsahin@gmail.com
- Phone: +905054431852
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.