Clinical trial Recruiting at 1 site Interventional Ages 18 to 65

Comparing different doses of truncal blocks for arm surgeries

Official title: Comparison of the Anesthetic and Analgesic Efficacy of Selective Truncal Blocks at Different Volumes in Upper Extremity Orthopedic Surgeries

Run by Gaziosmanpasa Research and Education Hospital · NCT06664203 · Data updated 2026-11-12

This study is testing different amounts of local anesthesia for arm surgeries to see which dose works best for pain relief and how quickly it takes effect.

Quick facts

Study typeInterventional
Ages18 Years to 65 Years
SexAll
Enrollment60 (estimated)
SponsorGaziosmanpasa Research and Education Hospital
Government
Locations1 site (Istanbul)
StatusRecruiting
StartedNovember 1, 2024
Main results expectedDecember 1, 2025
Study endsDecember 1, 2025
Registry record updatedMarch 5, 2025
Trial IDNCT06664203 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18-65 with ASA scores of 1-2 undergoing upper extremity orthopedic surgeries, excluding shoulder procedures.

Probably not a fit

Patients with severe pulmonary disease, uncontrolled diabetes, or those with allergies to local anesthetics may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the effectiveness of selective truncal blocks using varying doses and volumes of local anesthetic for anesthesia in patients undergoing surgeries of the hand, wrist, forearm, and elbow. The primary focus is on the onset times of motor and sensory blocks, with successful anesthesia defined as the completion of surgery under regional anesthesia. Secondary outcomes will assess motor block duration, analgesia duration, and potential complications associated with the procedure.

Why it matters

Potential benefit: If successful, this approach could enhance pain management and reduce complications during upper limb surgeries.

How similar studies have gone: Previous studies have shown promising results with peripheral nerve blocks in upper extremity surgeries, indicating that this approach is supported by existing evidence.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* ASA 1-2
* Body Mass Index (BMI) of 18-35 kg/m²
* Age: 18-65 years -Patients undergoing all upper extremity orthopedic surgeries, except shoulder surgeries (distal humerus, elbow, forearm, hand, and wrist), will be included. -

Exclusion Criteria:

* Patient refusal
* Pregnancy or breastfeeding
* Severe pulmonary disease
* Contralateral diaphragm paralysis
* Nerve injury secondary to trauma
* Neuromuscular disease
* Peripheral neuropathy
* Bleeding diathesis
* Allergy to local anesthetics and dexamethasone
* Uncontrolled diabetes mellitus
* Morbid obesity with BMI \>35
* Severe cardiovascular, renal, or hepatic disease
* Infection at the site of the nerve block

Where it's running

  • Gaziosmanpasa Research and Training Hospital
    Istanbul, Turkey (Türkiye)
    Recruiting

Study contacts

  • Principal investigator: Serpil Sehirlioglu, MD — Gaziosmanpasa Research and Training Hospital
  • Study coordinator: serpil Sehirlioglu, MD
  • Email: drserpilsahin@gmail.com
  • Phone: +905054431852

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.