Comparing devices that measure the eye's lipid layer thickness
Official title: Comparative Assessment of Lipid Layer Thickness Measurements Across Three Devices and Their Correlation With Clinical Indicators in Dry Eye Disease
Run by Indiana University · NCT07579130 · Data updated 2026-11-12
This test compares three common devices to see which gives the most consistent lipid layer thickness measurements in people with dry eye.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 100 Years |
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | Indiana University Academic / other |
| Locations | 1 site (Bloomington, Indiana) |
| Status | Recruiting |
| Started | April 1, 2026 |
| Main results expected | December 20, 2028 |
| Study ends | December 20, 2028 |
| Registry record updated | May 11, 2026 |
| Trial ID | NCT07579130 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults with a diagnosis of dry eye disease who can attend in-person testing at the study location are the ideal participants.
✕Probably not a fit
People without dry eye, those unable to attend the clinic in Bloomington, Indiana, or patients whose care requires therapeutic rather than diagnostic interventions are unlikely to benefit directly.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study collects lipid layer thickness (LLT) measurements from three clinical devices—LipiView, Omnicad, and the Bruder Ocular Surface Analyzer—in people diagnosed with dry eye. Participants will have LLT measured on each device and standard clinical dry eye signs and symptom scores recorded. The analysis will quantify agreement between devices and determine which device's LLT best correlates with established indicators of disease severity. Results will show consistency and clinical relevance of each device's measurements to inform device selection in practice.
Why it matters
Potential benefit: If one device shows more consistent measurements and stronger links to clinical signs, clinicians could use it to improve diagnostic clarity and monitoring for patients with dry eye.
How similar studies have gone: Previous research has used these devices and found variable agreement between instruments, but no single device has been universally established as superior.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Dry eye disease Exclusion Criteria: * None
Where it's running
-
Atwater Eye Care Center
Bloomington, Indiana, United States Recruiting
Study contacts
- Study coordinator: Anna Tichenor
- Email: annatich@iu.edu
- Phone: 8128550520
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.