Comparing cognitive and motor rehabilitation methods for multiple sclerosis
Official title: Isolated Versus Combined Cognitive and Motor High-tech Rehabilitation in Patients with Multiple Sclerosis
Run by Universita di Verona · NCT06820125 · Data updated 2026-11-12
This study tests different rehabilitation methods for people with multiple sclerosis to see which one helps improve thinking and movement skills the best.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 48 (estimated) |
| Sponsor | Universita di Verona Academic / other |
| Locations | 1 site (Verona, verona) |
| Status | Recruiting |
| Started | July 5, 2023 |
| Main results expected | July 5, 2023 |
| Study ends | July 5, 2026 |
| Registry record updated | February 11, 2025 |
| Trial ID | NCT06820125 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are individuals with multiple sclerosis experiencing mild to moderate cognitive and motor deficits.
✕Probably not a fit
Patients with other neurological disorders, major psychiatric conditions, or those who have recently undergone rehabilitation may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This project investigates the effects of high-tech neurorehabilitation interventions on cognitive and motor disabilities in individuals with multiple sclerosis. Participants will be assigned to one of three groups: cognitive rehabilitation, motor rehabilitation, or a combined approach. The study aims to determine which intervention is most effective and to identify patient profiles that benefit the most from each type of rehabilitation. By analyzing outcomes, the research seeks to enhance rehabilitation strategies for MS patients.
Why it matters
Potential benefit: If successful, this study could lead to more effective rehabilitation strategies tailored to the needs of multiple sclerosis patients.
How similar studies have gone: Other studies have shown promise in using combined cognitive and motor rehabilitation approaches, suggesting potential for success in this area.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * presence of mild (one or two neuropsychological tests below the cut-off score, 5th percentile) or severe (more than two neuropsychological tests below the cut-off score, 5th percentile) cognitive impairment, * mild to moderate walking disability with Expanded Disability Status Scale (EDSS) between 3 and 6, * no relapse or associated steroid use in the past three months, * adequate visual and auditory capacity to operate computer software. Exclusion Criteria: * presence of other neurological disorders than MS, * major psychiatric disorders, * high levels of anxiety and/or depression (score\>20 for Depression scale and up to 14 for Anxiety scale on Italian adaptation of the Depression, Anxiety and Stress Scale (DASS-21), * substance abuse, * any type of rehabilitation intervention in the month prior to recruitment * pharmacological therapy not well defined and/or changed during the study * presence of paroxysmal vertigo * lower limb botulinum toxin injections within the previous 12 weeks
Where it's running
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Sezione medicina fisica e riabilitativa dipartimento di neuroscienze
Verona, verona, Italy Recruiting
Study contacts
- Study coordinator: Valentina Varalta
- Email: valentina.varalta@univr.it
- Phone: 045 8124956
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.