Comparing cognitive and motor rehabilitation methods for multiple sclerosis
Isolated Versus Combined Cognitive and Motor High-tech Rehabilitation in Patients with Multiple Sclerosis
This study tests different rehabilitation methods for people with multiple sclerosis to see which one helps improve thinking and movement skills the best.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 48 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Universita di Verona Academic / other |
| Locations | 1 site (Verona, verona) |
| Trial ID | NCT06820125 on ClinicalTrials.gov |
What this trial studies
This project investigates the effects of high-tech neurorehabilitation interventions on cognitive and motor disabilities in individuals with multiple sclerosis. Participants will be assigned to one of three groups: cognitive rehabilitation, motor rehabilitation, or a combined approach. The study aims to determine which intervention is most effective and to identify patient profiles that benefit the most from each type of rehabilitation. By analyzing outcomes, the research seeks to enhance rehabilitation strategies for MS patients.
Who should consider this trial
Good fit: Ideal candidates are individuals with multiple sclerosis experiencing mild to moderate cognitive and motor deficits.
Not a fit: Patients with other neurological disorders, major psychiatric conditions, or those who have recently undergone rehabilitation may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more effective rehabilitation strategies tailored to the needs of multiple sclerosis patients.
How similar studies have performed: Other studies have shown promise in using combined cognitive and motor rehabilitation approaches, suggesting potential for success in this area.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * presence of mild (one or two neuropsychological tests below the cut-off score, 5th percentile) or severe (more than two neuropsychological tests below the cut-off score, 5th percentile) cognitive impairment, * mild to moderate walking disability with Expanded Disability Status Scale (EDSS) between 3 and 6, * no relapse or associated steroid use in the past three months, * adequate visual and auditory capacity to operate computer software. Exclusion Criteria: * presence of other neurological disorders than MS, * major psychiatric disorders, * high levels of anxiety and/or depression (score\>20 for Depression scale and up to 14 for Anxiety scale on Italian adaptation of the Depression, Anxiety and Stress Scale (DASS-21), * substance abuse, * any type of rehabilitation intervention in the month prior to recruitment * pharmacological therapy not well defined and/or changed during the study * presence of paroxysmal vertigo * lower limb botulinum toxin injections within the previous 12 weeks
Where this trial is running
Verona, verona
- Sezione medicina fisica e riabilitativa dipartimento di neuroscienze — Verona, verona, Italy (Recruiting)
Study contacts
- Study coordinator: Valentina Varalta
- Email: valentina.varalta@univr.it
- Phone: 045 8124956
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.