Comparing chlorhexidine and saline for cleaning during colorectal cancer surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the effectiveness of chlorhexidine gluconate compared to saline for flushing the surgical area during colorectal cancer surgeries. It focuses on measuring outcomes such as surgical site infections and postoperative complication rates. Patients aged 18-85 with resectable colorectal tumors will be included, while those with distant metastasis or significant prior surgeries will be excluded. The intervention involves intraoperative irrigation of the surgical site with either chlorhexidine or saline.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Patients aged 18-85 years,
2. Patients with surgically resectable colorectal tumors confirmed by CT/MRI before surgery
3. All patients had a performance status score of 0 or 1 in the Eastern Tumor Cooperative group
4. American Society of Anesthesiology grade I-III

Exclusion Criteria:

1. The tumor may have distant metastasis
2. History of previous abdominal surgery
3. The patient has a history of other malignant tumors diagnosed in the past 5 years and has received radiotherapy and chemotherapy in the past
4. There are obvious contraindications to surgery (obvious abnormal liver and kidney function, pregnancy)
5. Participated in other clinical trials within the past 6 months

Where it's running

• Nanchong Central Hospital
  Nanchong, Sichuan, China Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.