Comparing bowel preparation methods for colonoscopy in patients with Crohn's and Ulcerative Colitis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the effectiveness and tolerability of two bowel preparation laxatives, oral sulfate solution (OSS) and 2L polyethylene glycol (PEG) solution, in individuals with inflammatory bowel disease (IBD) who are scheduled for colonoscopy. By comparing these two preparations, the study seeks to determine which option provides better outcomes for patients undergoing this procedure. Participants will be outpatients aged over 18 with Crohn's disease or ulcerative colitis. The study is designed to enhance the colonoscopy experience for these patients by identifying the more effective and tolerable preparation method.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Crohn's disease or ulcerative colitis patients scheduled or about to be scheduled for colonoscopy.
2. Age \> 18 years
3. Out-patients

Exclusion Criteria:

1. Prior subtotal or total colorectal resection
2. Contraindications to use of 2L polyethylene glycol (2L-PEG) or Oral Sulfate Solution (OSS): Known renal insufficiency, congestive heart failure, cirrhosis, severe electrolyte imbalance.
3. Colonoscopy being repeated because of poor preparation in the preceding six months.
4. Allergies to the employed bowel preparations
5. Toxic megacolon, ileus, suspected or diagnosed bowel obstruction.
6. IBD patients thought to be too sick to undergo a full colonoscopy preparation in the opinion of the investigator/treating physician; hospitalized crohn's disease or ulcerative colitis patients.
7. Pregnancy

Where it's running

• University of Manitoba
  Winnipeg, Manitoba, Canada Recruiting

Study contacts

• Study coordinator: Jane Castelli
• Email: jcast@mcmaster.ca
• Phone: 289-880-3609

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.